Results 141 to 150 of about 104,722 (311)
Application of mesh-free methods in the wing rigidity analysis to support automation of UAV design
Modern aircraft design, including both manned aircraft and unmanned aerial vehicles (UAVs), faces computational challenges balancing aerodynamic efficiency, structural integrity, and weight optimization within practical timeframes.
Vadym Pasko, Sviatoslav Yutskevych
doaj +1 more source
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Design and Design Automation of Rectification Logic for Engineering Change
[[abstract]]In a later stage of a VLSI design, it is quite often to modify a design implementation to accommodate the new specification, design errors, or to meet design constraints. In addition to meet the design schedule for the new implementation, the
Cheng-Hung Lin;Yung-Chang Huang;Shih-Chieh Chang;Wen-Ben Jone
core +1 more source
This paper presents an improved deep reinforcement learning-based (DRL) approach for end-to-end models using a Graph Neural Network(GNN). The proposed method aims to improve end-to-end deep Q learning with a GNN by decomposing the GNN-based Q-network ...
Tianchen Zhou +5 more
doaj +1 more source
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Counting degrees of freedom for developable Bézier surface design
[[abstract]]This paper investigates the number of degrees of freedom for geometric design of developable Be´zier surfaces. The conditions for developability are derived geometrically from the de Casteljau algorithm and expressed as a set of equations ...
Chu, Chih-Hsing
core +1 more source

