Results 61 to 70 of about 26,446 (263)

Lateral Seismic Response and Self-Centering Performance of a Long-Span Railway Continuous Beam-Arch Bridge

Shock and Vibration, 2020
Based on the seismic isolation design concept of functional separation, a seismic isolation system with bearings and braces combination for railway bridge was proposed.
Yan Shi, Zhanhong Zhang, Hongguo Qin, Xiangyu Zhao, Xiong Yang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A novel semi-flexible coaxial nozzle based on fluid dynamics effects and its self-centering performance study

Scientific Reports
Coaxial nozzles are widely used to produce fibers with core–shell structures. However, conventional coaxial nozzles cannot adjust the coaxiality of the inner and outer needles in real-time during the fiber production process, resulting in uneven fiber ...
Yu Li, Shilei Li, Xiaobo Du, Haijun Qu, Jianping Wang, Pingyan Bian, Haiguang Zhang, Shuisheng Chen   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Centering PrEP: Utilizing ADAPT-ITT to inform group PrEP care for sex workers in Chicago

BMC Public Health
Background Sex workers, those who trade sex for monetary or nonmonetary items, experience high rates of HIV transmission but have not been adequately included in HIV prevention and Pre-Exposure Prophylaxis (PrEP) adherence program development research ...
Randi Beth Singer, Janelli Barrow, Amy K. Johnson, Jessica Zemlak, Natasha Crooks, Sarah Abboud, Douglas Bruce, Noel Green, Jahari Stamps, Jennifer Neely, Susan G. Sherman, Crystal L. Patil, Alicia K. Matthews   +12 more
doaj   +1 more source

Evaluation of dentin thickness preservation and the efficiency of instrumentation between traditional and guided endodontic access in mandibular central incisors

Journal of Oral Biology and Craniofacial Research
Introduction: Tooth substance loss during endodontic treatment is a major concern, especially in mandibular incisors due to their minimal tooth volume. Template-guided access cavities help preserve dentin and improve instrument centering.
Pooja R. Kesharani, Shalini D. Aggarwal, Nishtha K. Patel, Jhanvi Patel, Ankita Bansal, Naman Patel   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Study of Failure Mode and Ultimate Bearing Capacity for Self-Centering SMA Connection

Buildings
An innovative self-centering shape memory alloy (SMA) connection that is used in a steel frame beam-column joint was developed to improve the energy dissipative capacity and self-centering capacity, and reduce the residual deformation.
Xiaozhu Fu, Shangwen Liu, Chaobin Jin, Shujun Hu   +3 more
doaj   +1 more source