Results 61 to 70 of about 4,466,204 (357)

Influence of the design concept of an experimental demonstration model of a rocket design element on the process of heat and mass transfer

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
A conceptual design of an experimental demonstration model of three-layer structure of a launch vehicle body is proposed, based on the replacement of aluminum honeycomb filler with an energy-related material, in particular, based on composite solid ...
V. I. Trushlyakov   +2 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Culture and concept design : a study of international teams [PDF]

open access: yes, 2011
This paper explores the relationship between culture and performance in concept design. Economic globalisation has meant that the management of global teams has become of strategic importance in product development.
Grierson, Hilary   +3 more
core  

An approach to relate business and application services using ISDL [PDF]

open access: yes, 2005
This paper presents a service-oriented design approach that allows one to relate services modelled at different levels of granularity during a design process, such as business and application services.
Dijkman, Remco   +2 more
core   +5 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Path Planning for Highly Automated Driving on Embedded GPUs

open access: yesJournal of Low Power Electronics and Applications, 2018
The sector of autonomous driving gains more and more importance for the car makers. A key enabler of such systems is the planning of the path the vehicle should take, but it can be very computationally burdensome finding a good one.
Jörg Fickenscher   +4 more
doaj   +1 more source

The application of multi-objective robust design methods in ship design [PDF]

open access: yes, 1999
When designing large complex vessels, the evaluation of a particular design can be both complicated and time consuming. Designers often resort to the use of concept design models enabling both a reduction in complexity and time for evaluation.
Coates, Graham   +2 more
core  

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Concept Design and Testing of Multi-nozzle Water Mist Fire Suppression System [PDF]

open access: yes, 2010
In this work a flexible design of multi-nozzle arrangement of water mist fire suppression system was studied. The source of fire was a 65 mm diameter cooking oil fire.
Ariasa, I. G. (I)   +3 more
core  

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