Results 31 to 40 of about 4,260,477 (269)

Future Design Phenomenon: Effect of Metronome

open access: yesRUDN Journal of Philosophy, 2023
The article is dedicated to the phenomenon of designing future in the paradigm of objective reality. Based on the I. Prigozhin’s conclusions on the process of coherence of separate parts into a whole through the establishment of a common development pace
Natalia A. Lukianova, Oksana A. Skalnaya
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

An Improved Method of Failure Mode Analysis for Design Changes [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityCustomers and market changes behaviour are a large part of the product creation and modification. Though, design changes introduce new potential failures into the products.
Laurenti, R., Rozenfeld, H.
core  

Mitigating the Piston Effect in High-Speed Hyperloop Transportation: A Study on the Use of Aerofoils

open access: yesEnergies, 2021
The Hyperloop is a concept for the high-speed ground transportation of passengers traveling in pods at transonic speeds in a partially evacuated tube. It consists of a low-pressure tube with capsules traveling at both low and high speeds throughout the ...
Aditya Bose, Vimal K. Viswanathan
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Ultra-wideband RCS reduction based on reflection cancellation and tunable absorption

open access: yesAIP Advances
This study proposes an ultra-wideband radar cross section (RCS) reduction technique based on reflection phase interference cancellation and tunable absorption. The operational frequency band of the combined structure is enhanced by uniting two overlapped
Xianliang Zeng   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

The Complete Design in the Composite Face Paradigm: Role of Response Bias, Target Certainty, and Feedback

open access: yesFrontiers in Human Neuroscience, 2014
Some years ago an improved design (the complete design) was proposed to assess the composite face effect in terms of a congruency effect, defined as the performance difference for congruent and incongruent target to no-target relationships (Cheung et al.,
Günter eMeinhardt   +2 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

The effect of generative design and topology optimization on the design and manufacturing of components in additive manufacturing

open access: yesIncertitudes et Fiabilité des Systèmes Multiphysiques
Additive manufacturing, has shown great promises, offering unexpectable design freedom and manufacturing flexibility. but traditional design methodologies cannot fully exploit the functionality of am. this study explores the impact of generative
Omar Lkadi   +2 more
doaj   +1 more source

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