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Protein engineering and design

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1989
Abstract Rapid advances in site-directed mutagenesis and total gene synthesis combined with new expression systems in prokaryotic and eukaryotic cells have provided the molecular biologist with tools for modification of existing proteins to improve catalytic activity, stability and selectivity, for construction of chimeric molecules ...
Blundell, T L   +16 more
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Systemic Design Engineering

INCOSE International Symposium, 2017
AbstractThe Concept Phase of Systems Engineering, also known as Design, is most critical for it determines most of the cost, complexity and value of a system. Given the interdisciplinary nature of Design, it is no wonder that a wide variety of tools and approaches have been developed to aid in addressing design problems.
Jon Wade   +2 more
openaire   +1 more source

Hypermedia and engineering design

New Review of Hypermedia and Multimedia, 1996
Building Services Engineering (bse) is an applied discipline within the construction industry. It is concerned with the design, installation, operation and maintenance of all mechanical and electri...
John D. Gilleard, Y. C. Lee
openaire   +1 more source

Engineering design of haemodialysers

Journal of Biomedical Engineering, 1983
Haemodialysis is a widely used treatment for chronic and acute renal failure and relies on the diffusion of solutes and water in a mass exchanger or haemodialyser. The design concepts of haemodialysers are discussed together with limitations of existing design solutions and work on the optimization of design reviewed.
N A, Hoenich, D N, Kerr
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Designing the Design Engineer

Journal of Professional Issues in Engineering, 1989
The modern engineering curriculum has evolved to be heavily weighted with science and analysis. Recent concern with the need for instruction in design has led to the introduction of capstone design courses. These courses give the student an opportunity to produce a design, using the scientific principles and analytic methods learned previously. However,
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Engineering design of macromodules

Proceedings of the April 18-20, 1967, spring joint computer conference on - AFIPS '67 (Spring), 1967
Macromodules are intended for assembly into a wide variety of computer structures with as few restrains on the designers' choice of the geometry of the machine as it is practical to require. The goal of geometric flexibility makes the problem of reliably interconnecting the modules to communicate date more difficult than usual.
Asher Blum   +2 more
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Evolution as Design Engineer

2003
Exponential growth in digital information gathering, storage, and processing capabilities for biological data herald a new age of biology, when entire biological systems can potentially be understood. In order to facilitate human understanding of electronic components, the electronic design automation (EDA) industry has developed clean abstractions and
David L. Dill, Patrick Lincoln
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Engineering Design as Research

2012
Research is defined as an activity that creates new knowledge. This is often misunderstood in the engineering community as necessarily requiring a scientific contribution that advances the theory of some matter related to engineering materials or processes.
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Engineering a designer immunotherapy

Science, 2018
Tailoring cytokine selectivity by engineering receptor-ligand pairs circumvents ...
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