Results 241 to 250 of about 20,506,281 (310)

Letter to the editor regarding "Risk factor analysis for growing pains in children: results of parental survey". [PDF]

J Child Orthop
Fallahi S, Silva-Mendoza D.
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Human factors methods for designing safe health information technology: what do the experts think? [PDF]

J Am Med Inform Assoc
Awad S, Begg R, Loveday T, Baillie A, Baysari MT.   +4 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Cardiometabolic risk burden and associated behaviours in schoolchildren aged 7-10 years from public urban schools in the Federal District, Brazil. [PDF]

PLoS One
Diogo SS, Gubert MB, Gonçalves VSS, do Carmo AS, Melo GRDAE, Oliveira GAL, Toral N.   +6 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Adolescents' Perspectives on Uptake, Engagement, and Implementation to Inform the Development of a Preventive Transdiagnostic Digital Mental Health Intervention: Qualitative Interview Study. [PDF]

J Med Internet Res
Hirsig A, Walder N, Häfeli XA, Schmidt SJ.   +3 more
europepmc   +1 more source

Shifting Skills in Robot-Assisted Surgery: Case Study With Interdisciplinary Perspectives for Human Factors and Career Research. [PDF]

JMIR Hum Factors
Ellwart T, Birke J, Paul JT.
europepmc   +1 more source

Multi-objective optimization of light guide column injection molding process using RSM and NSGA‑II with numerical verification. [PDF]

PLoS One
Xu H.
europepmc   +1 more source