Results 51 to 60 of about 116,123 (240)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Design for manufacture and sustainability in new product development [PDF]

open access: yes, 2010
Design for manufacture is well recognised by industry and is about optimising design to aid production. Today there is a significant and growing trend of recognising what happens to a product once its user phase has finished.
De Coster, R   +3 more
core  

Investigations of generic self disassembly using shape memory alloys [PDF]

open access: yes
Industrial recycling is a practice of growing importance while impending `Take Back' European legislation and economic pressures are increasing. Landfill sites are becoming exhausted and the industry could benefit from a novel approach to recycling pre ...
Billett, EH   +3 more
core   +1 more source

On the Collaboration of an Automatic Path-Planner and a Human User for Path-Finding in Virtual Industrial Scenes [PDF]

open access: yes, 2010
This paper describes a global interactive framework enabling an automatic path-planner and a user to collaborate for finding a path in cluttered virtual environments.
Fourquet, Jean-Yves, Ladevèze, Nicolas
core   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

Human resource strategy in disassembly for remanufacturing [PDF]

open access: yes, 2013
Studies on product disassembly for remanufacturing using strategic perspective have been overlooked in current studies. This research uses a strategic approach to examine how product, process and organisational design affect disassembly strategies among ...
Bititci, Umit S.   +2 more
core  

State of the art of plastic sorting and recycling : Feedback to vehicle design [PDF]

open access: yes, 2007
Today car manufacturers are beginning to integrate recycling constraints in the first stages of the design of a new car due to their concern regarding the effects of car design on the recovery of material after End-of-Life Vehicle treatment.
ABRAHAM, F   +6 more
core   +4 more sources

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

open access: yesAdvanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin   +14 more
wiley   +1 more source

Evaluasi Kemudahan Pembongkaran Produk untuk Perbaikan (Product Repair) [PDF]

open access: yes, 2018
Electronic wasteis a waste that comes from household products that use electricity and have reached the end of life because it has been damaged, old and may not be used anymore.
, Ida Nursanti, ST., M.Eng.Sc   +1 more
core  

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