Results 81 to 90 of about 19,879 (265)
Jixie chuandong, 2007 Conjugate cam mechanism is a kind of geometrical-closed cam mechanism.The high precision of design,manufacture and assembly is required.Due to multiple parts engaged,the complex design and miscelleanous calculation of cam profiles has barriered its wide ...
唐善华
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Design and construction of a two-story laminated bamboo lumber structure in Hong Kong
Sustainable StructuresThis paper presents a technical case study on the structural design and assembly of a two-story community liaison center utilizing Laminated Bamboo Lumber (LBL) as the primary structural and architectural material.
Peng Zhou +12 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar +2 more
wiley +1 more source
Strength Analysis on Propel Gearbox of Hydraulic Excavator
Jixie chuandong, 2019 Taking the external load distribution on sprocket wheel and meshing forces of planetary gear trains into account， the strength of case and the three-stage planet carrier assembly under three working conditions is analyzed by using Abaqus， comparison and ...
Wei Zou
doaj
BuildingsCurrently, the global construction industry is facing challenges of stagnant efficiency and cost overruns. The potential of modular construction has not been fully unleashed due to the disconnection between design and manufacturing. This paper proposes a
Meng Wang +3 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar +7 more
wiley +1 more source