Results 201 to 210 of about 10,110,846 (278)

Conversion-intent PD-1-based chemoimmunotherapy restores surgical feasibility in borderline resectable or unresectable non-head-and-neck cutaneous squamous cell carcinoma. [PDF]

Oncologist
Qian W, Jia D, Wu H, Zou H, Xu H, Li T.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Selective legibility: From material readout to machine agency. [PDF]

Innovation (Camb)
Chen B.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating user experiences with an AI chatbot for health-related social needs: A cross-sectional mixed methods study. [PDF]

PLOS Digit Health
Sezgin E, Jackson DI, Hussain SA, Kocaballi AB, Richardson C, Skeens M, Fosler-Lussier E, Ewing AP, Donneyong M, Pai A.   +9 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Allocation Policy Implementation During a Severe Chemotherapy Shortage.

JAMA Netw Open
Blackstone EC, Wang Y, Inyang EA, Shuman AG, Casey M, Abel GA, Hantel A.   +6 more
europepmc   +1 more source

Accidental and Intentional Drug Poisoning Mortality in Older Adults in Spain: Nationwide Trends, 2001-2022. [PDF]

Mayo Clin Proc Innov Qual Outcomes
Donat M, Ramírez-Alcázar C, Giné F, Sordo L, Martínez Torre S, Belza MJ, Barrio G, Politi J.   +7 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Understanding the impact of perceived emotional valence of eco-labels for novel food products on consumer preferences, visual attention, and cognition - a multimodal study using EEG and eye tracking. [PDF]

Front Psychol
Parasuram U, Yue C, Steede G, Gallardo RK, Eisenreich BR, Clark M.   +5 more
europepmc   +1 more source