Results 251 to 260 of about 13,948,543 (335)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Deep learning models built from PSMA PET of the primary tumor can predict synchronous and metachronous prostate cancer metastases. [PDF]

open access: yesPLoS One
Juarez Casillas JE   +11 more
europepmc   +1 more source

Influence of work-life balance, personal fulfillment, and job satisfaction on emigration intent among pharmacists: A multi-sectoral survey. [PDF]

open access: yesExplor Res Clin Soc Pharm
Ihekoronye MR   +7 more
europepmc   +1 more source

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