Results 31 to 40 of about 10,110,846 (278)

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben   +4 more
wiley   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann   +8 more
wiley   +1 more source

Educational Rationale Metadata for Learning Objects

open access: yesCanadian Journal of Learning and Technology, 2002
Instructors searching for learning objects in online repositories will be guided in their choices by the content of the object, the characteristics of the learners addressed, and the learning process embodied in the object.
Tom Carey   +2 more
doaj   +1 more source

Bridging designers' intentions to outcomes with constructivism [PDF]

open access: yesProceedings of the 8th ACM Conference on Designing Interactive Systems, 2010
This exploratory study investigates the value of constructivist theory for the field of interaction design. In this paper we explore how designer intentions and outcomes can be expressed in constructivist terms, and how constructivism can describe the relationship of design intentions to outcomes.
Kevin Muise, Ron Wakkary
openaire   +3 more sources

Revisiting the Design Intent Concept in the Context of Mechanical CAD Education [PDF]

open access: yes, 2017
Design intent is generally understood simply as a CAD model’s anticipated behavior when altered. However, this representation provides a simplified view of the model’s construction and purpose, which may hinder its general understanding and future ...
Company, Pedro   +10 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

An Element-Based Iterative Intent Understanding Method for Complex Product Conceptual Design

open access: yesApplied System Innovation
Product design constitutes an iterative process centered on user requirements. In this process, user requirements are collected, interpreted by designers and transformed into design objectives, which are then refined through solution generation and ...
Zeyuan Yu   +5 more
doaj   +1 more source

From Algorithmic Intent to Accountable Assembly: A Computational Delivery Framework for Digital Architecture [PDF]

open access: yesE3S Web of Conferences
Parametric design has transformed architectural authorship from form-making to the orchestration of generative systems governed by performance, structure, and spatial logic.
Lyu Ruijie, Zhao Jing, Chen Guoliang
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz   +6 more
wiley   +1 more source

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