Results 141 to 150 of about 3,978,056 (320)

Review on accelerated life testing plan to develop predictive reliability models for electronic components based on design‐of‐experiments [PDF]

, 2023
Fatima‐Ezahra Indmeskine, Laurent Saintis, Abdessamad Kobi   +2 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Optimization analysis of active solar still using design of experiment method [PDF]

, 2020
Mohammad Abu Abbas, Malik Al-Abed Allah, Qias Nedal Al-Oweiti   +2 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

An Experimental Design Approach for Producing Curcumin-Loaded Solid Lipid Nanoparticles

Pharmaceuticals
Background/Objectives: Curcumin has well-established efficacy in a variety of disorders due to its prominent antioxidant, antiaging, anti-inflammatory, chemosensitizing, and anticancer activities.
Ongun Mehmet Saka, Cemre İrem Aygüler, Neval Sevinç Özdemir, Bilge Sürücü, Egemen Çakırlı, Emirhan Nemutlu, Gülen Melike Demirbolat   +6 more
doaj   +1 more source

Optimizing Nanosuspension Drug Release and Wound Healing Using a Design of Experiments Approach: Improving the Drug Delivery Potential of NDH-4338 for Treating Chemical Burns [PDF]

Tomas L. Roldan, Shike Li, Christophe Guillon, Ned D. Heindel, Jeffrey D. Laskin, In Heon Lee, Dayuan Gao, Patrick J. Sinko   +7 more
openalex   +1 more source

DESIGN AND EXPERIMENT OF A SELF-PROPELLED JUJUBE COLLECTION STRIP PICK-UP MACHINE [PDF]

, 2023
Fengkui ZHANG, Wenxi SHAO, Jikui ZHU, Ting Zhang, Shijie Zhao, Ping Li   +5 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Artificial neural network for optimizing the formulation of curcumin-loaded liposomes from statistically designed experiments

, 2022
Ibilola Mary Cardoso-Daodu, Margaret O. Ilomuanya, Andrew Nosakhare Amenaghawon, Chukwuemeka P. Azubuike   +3 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source