Results 221 to 230 of about 4,507,524 (283)

Optimization of Eudragit RS100 Nanocapsule Formulation for Encapsulating Perillyl Alcohol and Temozolomide Using Design of Experiments. [PDF]

ACS Nanosci Au
Padilha Lorenzett AK, Babinski TP, de Lima VA, Mainardes RM.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Optimization of Tibial Stem Geometry in Total Knee Arthroplasty Using Design of Experiments: A Finite Element Analysis. [PDF]

Bioengineering (Basel)
Lee HH, Hong HT, Kim JK, Koh YG, Park KK, Kang KT.   +5 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

A Design of Experiments Approach for Enhancing Room Temperature Stability of a Lyophilised and Paper-Based Bacterial Cell-Free System. [PDF]

Bioengineering (Basel)
Shivakumar T, Clark J, Goode A, Anyanwu VE, Williams PM.   +4 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Optimization of Solid Lipid Nanoparticle Formulation Using Design of Experiments, PART I: <i>Strategic Tool for the Determination of Critical Parameters Regarding Formulation and Process</i>. [PDF]

Nanomaterials (Basel)
Cassayre M, Teles de Souza D, Claeys-Bruno M, Altié A, Piccerelle P, Sauzet C.   +5 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Spinal cord injury regenerative therapy development: integration of design of experiments. [PDF]

Neural Regen Res
Okano Y, Okano H, Kase Y.
europepmc   +1 more source

Efficient Process Development of Abiraterone Acetate by Employing Design of Experiments. [PDF]

ACS Omega
Komati SK, Madhra MK, Manda A, Venkata Annapurna SC, Senadi GC, Maruthapillai A, Maruthapillai A, Bandichhor R.   +7 more
europepmc   +1 more source