Results 221 to 230 of about 5,293,393 (391)

Optimization of Tibial Stem Geometry in Total Knee Arthroplasty Using Design of Experiments: A Finite Element Analysis. [PDF]

Bioengineering (Basel)
Lee HH, Hong HT, Kim JK, Koh YG, Park KK, Kang KT.   +5 more
europepmc   +1 more source

GCFR grid plate shield design confirmation experiment

, 1979
F.J. Muckenthaler, J. L. Hull, John J. Manning   +2 more
openalex   +2 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

A Design of Experiments Approach for Enhancing Room Temperature Stability of a Lyophilised and Paper-Based Bacterial Cell-Free System. [PDF]

Bioengineering (Basel)
Shivakumar T, Clark J, Goode A, Anyanwu VE, Williams PM.   +4 more
europepmc   +1 more source

Second Order Efficiency in the Sequential Design of Experiments [PDF]

, 1984
Robert W. Keener
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Direct Consideration of Process History During Intensified Design of Experiments Planning Eases Interpretation of Mammalian Cell Culture Dynamics. [PDF]

Bioengineering (Basel)
Kienzle S, Junghans L, Wieschalka S, Diem K, Takors R, Radde NE, Kunzelmann M, Presser B, Nold V.   +8 more
europepmc   +1 more source

Design of simulation experiments [PDF]

Kleijnen, J.P.C.
core   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Optimising Bioprinting Nozzles through Computational Modelling and Design of Experiments. [PDF]

Biomimetics (Basel)
Blanco JCG, Macías-García A, Rodríguez-Rego JM, Mendoza-Cerezo L, Sánchez-Margallo FM, Marcos-Romero AC, Pagador-Carrasco JB.   +6 more
europepmc   +1 more source