Results 131 to 140 of about 8,356,305 (300)
International Journal of Turbomachinery, Propulsion and PowerThe successful implementation of an airborne propulsion system based on hydrogen-powered fuel cell technology highly depends on the development of an efficient, lightweight and compact air supply compressor.
Alessandro Cappiello +2 more
doaj +1 more source
Enhancing the Thermostability of Rhizomucor miehei Lipase with a Limited Screening Library by Rational-Design Point Mutations and Disulfide Bonds. [PDF]
Appl Environ Microbiol, 2018 Li G, Fang X, Su F, Chen Y, Xu L, Yan Y.
europepmc +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Optimization of the Geometry of the Centrifugal Fan at Different Design Points
Applied SciencesThe optimization of the geometry of a centrifugal fan is performed at maximum power and high-efficiency design points (DPs) to improve impeller efficiency. Two design variables defining the shape of fan blade are selected for the optimization.
Paulius Ragauskas +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Previous discussions of pointing have largely evaded a central question: How is an actof pointing even recognized as communicative in the first place? Here I argue—building onclassic and recent work in pragmatics—that pointing is designed to deviate minimally from mereattending.
openaire +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The Provision Point Mechanism and Scenario Rejection in Contingent Valuation [PDF]
The provision point mechanism mitigates free-riding behavior in economic experiments. In two contingent valuation method surveys, we implement the provision point design.
Groothuis, Peter A., Whitehead, John C.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
THE DESIGN AND COMPARATIVE ECONOMIC PERFORMANCE OF ALTERNATIVE SECOND-BEST POINT/NONPOINT TRADING MARKETS [PDF]
There is considerable interest in the use of pollution trading between point and nonpoint sources to improve the cost-effectiveness of water pollution control, but little literature to guide the design of trading systems involving nonpoint sources.
Abler, David G. +3 more
core +1 more source