Results 91 to 100 of about 7,545,913 (316)
Jurnal ElemenMathematics education in Indonesia faces challenges primarily due to the limited problem-solving skills of students, prompting a need for effective teaching materials to enhance classroom learning.
Eka Kevin Alghiffari +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Strange bedfellows: Design research and behavioral design
, 2020 Behavioral design—the application of behavioral economics principles to real-world challenges—has achieved success across a variety of domains, yet its scale and effectiveness has been limited by its narrow focus on behavioral change to frame problems ...
Ruth Schmidt, Schmidt, Ruth
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Technology Innovation Management Review, 2016 Infection prevention and control has been the subject of much study in medical and epidemiological research and a variety of best practice guidelines have been developed to support healthcare workers and related stakeholders.
Chantal Trudel +4 more
doaj
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Design Research and Object-Oriented Ontology
Open Philosophy, 2020 In this paper we recount several research projects conducted at ImaginationLancaster (http://imagination.lancs.ac.uk) a Design-led research laboratory, all of which consider Object-Oriented Ontology (OOO).
Lindley Joseph +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2010 This paper addresses the role of the designer as actor/agency working within and across flows of knowledge, perception and information for filtering, negotiating and mediating design decision making.
Shumack, Kaye (R8571)
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source