Results 91 to 100 of about 2,126,236 (343)

Modelling of impact damage and permanent indentation on laminate composite plate [PDF]

open access: yes, 2010
This paper deals with impact damage and permanent indentation modelling. A model enabling the formation of damages developing during a low velocity / low energy impact test on laminate composite panels has been elaborated.
Barrau, Jean-Jacques   +2 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Two-Stage Subspace Constrained Precoding in Massive MIMO Cellular Systems

open access: yes, 2015
We propose a subspace constrained precoding scheme that exploits the spatial channel correlation structure in massive MIMO cellular systems to fully unleash the tremendous gain provided by massive antenna array with reduced channel state information (CSI)
Lau, Vincent, Liu, An
core   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Product development process improvement: A review of Design Structure Matrix methods

open access: yesMATEC Web of Conferences, 2017
Iteration is an important characteristic of the design process. The Design Structure Matrix (DSM) is a powerful method allowing modelling, analysis, and optimisation of iterations in the design process.
Boudouh Toufik, Bendada Larbi
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

User-inspired design methodology using Affordance Structure Matrix (ASM) for construction projects

open access: yesMATEC Web of Conferences, 2017
Traditionally, design phase of construction projects is often performed with incomplete and inaccurate user preferences. This is due to inefficiencies in the methodologies used for capturing the user requirements that can subsequently lead to ...
Maheswari J. Uma   +2 more
doaj   +1 more source

Organization of the channel-switching process in parallel computer systems based on a matrix optical switch [PDF]

open access: yes
After a classification and analysis of electronic and optoelectronic switching devices, the design principles and structure of a matrix optical switch is described.
Golomidov, Y. V.   +3 more
core   +1 more source

Acoustic phonon transport through a double-bend quantum waveguide

open access: yes, 2007
In this work, using the scattering matrix method, we have investigated the transmission coefficients and the thermal conductivity in a double-bend waveguide structure.
Angelescu   +29 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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