Results 111 to 120 of about 2,126,236 (343)
Design Process Guide Method for Minimizing Loops and Conflicts
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2009 We propose a new guide method for developing an easy-to-design process for product development. This process ensures a smaller number of wasteful iterations and less multiple conflicts. The design process is modeled as a sequence of design decisions.
Tsuyoshi KOGA, Kazuhiro AOYAMA
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Conceptual Design of an Attachment Based Reconfigurable Machine Tool Using Design Structure Matrix [PDF]
, 2021 Ambrish Gupta
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FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Design Analysis Method for Multidisciplinary Complex Product using SysML
MATEC Web of Conferences, 2017 In the design of multidisciplinary complex products, model-based systems engineering methods are widely used. However, the methodologies only contain only modeling order and simple analysis steps, and lack integrated design analysis methods supporting ...
Liu Jihong, Wang Shude, Fu Chao
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On the formulation of a minimal uncertainty model for robust control with structured uncertainty [PDF]
In the design and analysis of robust control systems for uncertain plants, representing the system transfer matrix in the form of what has come to be termed an M-delta model has become widely accepted and applied in the robust control literature.
Belcastro, Christine M. +2 more
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Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Generalized companion matrix for approximate GCD
, 2011 We study a variant of the univariate approximate GCD problem, where the coefficients of one polynomial f(x)are known exactly, whereas the coefficients of the second polynomial g(x)may be perturbed.
Boito, Paola, Ruatta, Olivier
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Multibody dynamics for biologically inspired smart space structure [PDF]
, 2013 Structures in space are often just serving a single purpose. By developing a structure which is able to change it properties and adapt to changing environmental conditions, the costs of space missions can be decreased significantly.
Sinn, Thomas, Vasile, Massimiliano
core
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source