Results 91 to 100 of about 5,290,684 (266)
Zika Virus Alters the Viscosity and Cytokines Profile in Human Colostrum
Journal of Immunology Research, 2019 The resurgence of cases of Zika virus (ZIKV) infection, accompanied by epidemic of microcephaly in Brazil, has aroused worldwide interest in understanding the biological mechanisms of the virus that allow patient management and the viral dissemination ...
Ocilma B. de Quental +7 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
UNDERSTANDING LQ45 STOCKS (2021-2023) WITH K-MEANS CLUSTERING
BarekengThe primary aim of this study is to examine the use of K-Means clustering in analyzing LQ45 stocks from 2021 to 2023, utilizing data obtained from the Yahoo Finance platform. The analysis delves into key performance measures such as the price-to-earnings
Margareta Febe +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Trends in Mortality Due to Stroke in South America between 1990 and 2019
EpidemiologiaStroke is the second leading cause of death and disability in Latin America; however, few epidemiological studies have been conducted in South America.
Alexandre Castelo Branco Araujo +9 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BarekengThis study aimed to address the instability of the Indonesian stock market from 2021 to 2023 by analyzing the LQ45 index, a critical indicator of economic robustness and corporate performance.
Giovanny Theotista +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Digital Paradox when Future and Tradition Co-Exist Contemporary Fashion with Augmented Reality
ARCHive-SRNowadays fashion world has undergone significant transformations in the digital era, with technology playing a crucial role in various aspects. The digital era has transformed the fashion industry by redefining how fashion is produced, marketed, and ...
Olivia Gondoputranto +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source