Results 171 to 180 of about 277,468 (266)

Environmental psychology as the science of context: grand challenges for the next decade

Frontiers in Psychology
Francesco Ruotolo, Francesco Aletta
doaj   +1 more source

Spatial Studies in Augmented, Virtual, and Mixed Reality: Potentials, Challenges, and Requirements. [PDF]

KN J Cartogr Geogr Inf
Keil J, Korte A, Edler D, Dickmann F.
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

SCOPE and FRAME: Context-Specific Tools for Virtual Care Service Delivery in Rural and Remote Communities. [PDF]

Mayo Clin Proc Digit Health
Deason JP, Rahman A, Smith MO, McKinney V, Adams SJ, Mendez I.   +5 more
europepmc   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Virtual State Coupled Sliding Mode Control: An Energy Exchange Approach with Tunable Performance Trade-Off. [PDF]

Sensors (Basel)
Wang J, Wang J, Jing J, Zhao C, Zhang L.
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Real environment obstacle circular edge expansion design robot path planning based on ant colony algorithm. [PDF]

PLoS One
Li F, Yang M, Jo SN, Kim YC, Lyu Z.
europepmc   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Designing for Comfort in VR Public Speaking: How Avatar Realism and Natural Environments Shape User Experience and Stress Responses. [PDF]

Behav Sci (Basel)
Zhang H, Peng R, Wang S, Song H, Li Z.
europepmc   +1 more source