Results 41 to 50 of about 11,907 (270)

Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal‐Immunotherapy

Advanced Science, EarlyView.
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang, Shanshan Liang, Meng Wang, Tingfeng Zhang, Jinke Liu, Yuyuan Peng, Hao Fang, Lingna Zheng, Xiao He, Meng Wang, Luling Wu, Tony D. James, Wei Zhao, Bing Wang, Weiyue Feng   +14 more
wiley   +1 more source

Determination of Bayesian Cramér–Rao Bounds for Estimating Uncertainties in the Bio-Optical Properties of the Water Column, the Seabed Depth and Composition in a Coastal Environment

Remote Sensing, 2023
The monitoring of coastal areas using remote sensing techniques is an important issue to determine the bio-optical properties of the water column and the seabed composition. New hyperspectral satellite sensors (e.g., PRISMA, DESIS or EnMap) are developed
Mireille Guillaume, Audrey Minghelli, Malik Chami, Manchun Lei   +3 more
doaj   +1 more source

East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series [PDF]

, 2019
Academic geriatric medicine in Leicester . There has never been a better time to consider joining us. We have recently appointed a Professor in Geriatric Medicine, alongside Tom Robinson in stroke and Victoria Haunton, who has just joined as a ...
Agarwal, S., Bankart, J., Bannerjee, J., Bell, Katie, Brown, Jayne, Chen, F., Chen, L., Chung, E., Clague-Baker, Nicola, Conroy, Simon, Fallmann, Sarah, Haunton, Victoria, Kondova, D., Larkin, M., Martin, G., Northcott, Andy, O'Kelly, K., Oldridge, Louise, Panerai, R., Phelps, K, Psychoula, I., Raghavan, Raghu, Regen, E., Robinson, T. G., Stahl, Bernd Carsten, 1968-, Subramaniam, H., Triboan, D., Wildbur, D., Williamson, I., Wilson, A.   +29 more
core  

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Storytelling in design for social innovation and politics: a reading through the lenses of Hannah Arendt [PDF]

, 2017
The German philosopher Hannah Arendt believes that storytelling can be used to reopen the idea of public space and to facilitate dialogue/action amongst citizens aimed at attaining a more participative society.
Bertolotti, Elisa, Piredda, Francesca, Tassinari, Virginia   +2 more
core   +2 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Probabilistic sensitivity analysis of biochemical reaction systems [PDF]

, 2009
Sensitivity analysis is an indispensable tool for studying the robustness and fragility properties of biochemical reaction systems as well as for designing optimal approaches for selective perturbation and intervention. Deterministic sensitivity analysis
Dempsey, William P., Goutsias, John, Zhang, Hong-Xuan   +2 more
core   +1 more source

Transformation Teams Leading the Hispanic‐Serving Institutions Movement at HSI Community Colleges

New Directions for Community Colleges, EarlyView.
ABSTRACT The Department of Education defunded discretionary grant programs for enrollment‐based minority‐serving institutions (MSIs) on September 10, 2025, yet Hispanic‐serving institutions (HSIs) still exist and must continue to adapt to their growing population of Latine/x students.
Gina Ann Garcia, Flor Huerta, Julio R. Flores   +2 more
wiley   +1 more source

Absolute Vicarious Calibration, Extended PICS (EPICS) Based De-Trending and Validation of Hyperspectral Hyperion, DESIS, and EMIT

Remote Sensing
This study addresses the critical need for radiometrically accurate and consistent hyperspectral data as the remote sensing community moves towards a hyperspectral world. Previous calibration efforts on Hyperion, the first on-orbit hyperspectral sensors,
Harshitha Monali Adrija, Larry Leigh, Morakot Kaewmanee, Dinithi Siriwardana Pathiranage, Juliana Fajardo Rueda, David Aaron, Cibele Teixeira Pinto   +6 more
doaj   +1 more source

Demonstration, validation, and application of hyperspectral microscopy for the collection of cyanobacterial spectral signatures

Limnology and Oceanography: Methods, EarlyView.
Abstract Cyanobacterial and other algal blooms are an environmental concern in waterbodies worldwide. While these blooms are a nuisance for recreational activities, they can also be harmful to human and wildlife health when the algae produce and release toxins.
Natalie C. Hall, Adam C. Mumford, Aaron M. Goldfain, David W. Allen, E. Terrence Slonecker, Alisa Shtabnoy, Carl J. Legleiter, Sarah A. Spaulding   +7 more
wiley   +1 more source