Results 11 to 20 of about 13,029 (233)
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]
, 2015 Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David +8 more
core +6 more sources
Journal of Nepal Medical Association, 2021 Desmoid tumors most commonly occur in the anterior abdominal wall in approximately 50% of cases and are locally aggressive. We describe a case of a 38-year-old lady who was investigated as a case of gastrointestinal tumor.
Anup Chalise +2 more
doaj +1 more source
Desmoid-Type Fibromatosis [PDF]
Cancers, 2020 Desmoid tumors represent a rare entity of monoclonal origin characterized by locally aggressive behavior and inability to metastasize. Most cases present in a sporadic pattern and are characterized by a mutation in the CTNNB1 gene; while 5–15% show a hereditary pattern associated with APC gene mutation, both resulting in abnormal β-catenin accumulation
Dorian Yarih Garcia-Ortega +7 more
openaire +2 more sources
Diagnostic imaging and CEUS findings in a rare case of Desmoid-type fibromatosis. A case report [PDF]
, 2018 Desmoid-type fibromatosis (DF), also known as aggressive fibromatosis, is a locally aggressive benign fibroblastic neoplasm that can infiltrate or recur but cannot metastasize.
De Felice, Carlo +6 more
core +1 more source
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]
, 2015 BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio +9 more
core +1 more source
Mesenteric desmoid tumor of the interposed jejunal pouch after total gastrectomy
World Journal of Surgical Oncology, 2006 Background Desmoid tumor is a rare entity, and most desmoid tumors are located in abdominal wall or extra-abdominal tissues. Occurrence of desmoid tumor in mesentry is extremely rare.
Kinoshita Hiroyuki +3 more
doaj +1 more source
Clinical results of active surveillance for extra‐abdominal desmoid‐type fibromatosis
Cancer Medicine, 2023 Background The treatment of choice for desmoid‐type fibromatosis (DF) has been changed to active surveillance (AS). However, few studies have reported clinical outcomes of AS modality in Asian countries. This study aimed to clarify the significance of AS
Tomohisa Sakai +6 more
doaj +1 more source
Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]
, 2002 Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core +2 more sources
Development of multifocal extra‐abdominal desmoid fibromatosis after surgical resection
Clinical Case Reports, 2019 Multifocal fibromatosis is a rare entity. We report on two cases where multifocal disease developed after surgical resection. Chronic inflammation and repetitive trauma may be considered a risk factor for developing multifocal disease.
Brendon M. Bauer +2 more
doaj +1 more source
Journal of Medical Case Reports, 2018 Background Desmoid-type fibromatoses are rare benign and fibrous tumors that account for approximately 0.03% of total neoplasms. Within this category of neoplasms, pancreatic desmoid-type fibromatosis is an extremely rare subgroup, accounting for ...
Joseph Clarence Torres, Chen Xin
doaj +1 more source