Results 51 to 60 of about 10,008 (224)

Targeting Stem Cell Behavior in Desmoid Tumors (Aggressive Fibromatosis) by Inhibiting Hedgehog Signaling

Neoplasia: An International Journal for Oncology Research, 2013
Desmoid tumor (also called aggressive fibromatosis) is a lesion of mesenchymal origin that can occur as a sporadic tumor or a manifestation of the preneoplastic syndrome, familial adenomatous polyposis caused by a mutation in adenomatous polyposis coli ...
Ronak Ghanbari-Azarnier, Shingo Sato, Qingxia Wei, Mushriq Al-Jazrawe, Benjamin A. Alman   +4 more
doaj   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source

Feasibility of the Reconstruction with Fascia Lata Patch on the Abdominal Wall Defect After Resection of the Abdominal Desmoid Tumor

Clinical and Experimental Gastroenterology, 2020
Ayana Goto, Nobuhisa Matsuhashi, Takao Takahashi, Toshiyuki Tanahashi, Satoshi Matsui, Hisashi Imai, Yoshihiro Tanaka, Kazuya Yamaguchi, Kazuhiro Yoshida Department of Surgical Oncology, Gifu University School of Medicine, Gifu City 501-1194 ...
Goto A, Matsuhashi N, Takahashi T, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K, Yoshida K   +8 more
doaj  

Successful treatment of desmoid tumor of the chest wall with tranilast: a case report

Journal of Medical Case Reports, 2010
Introduction Desmoid tumor is characterized by infiltrative growth and local recurrence often occurs after surgery. To reduce the local recurrence rate, adjuvant therapy, such as radiotherapy and pharmacotherapy with cytotoxic agents, anti-estrogen ...
Hozumi Takahiro, Ogura Koichi, Nemoto Tetsuo, Goto Takahiro, Funata Nobuaki   +4 more
doaj   +1 more source

Long-term follow up of a patient with a recurrent desmoid tumor that was successfully treated with proton beam therapy: A case report and literature review

Clinical and Translational Radiation Oncology, 2021
Desmoid tumors are benign, but may have a locally invasive tendency that commonly results in local recurrence. Most occur on the body trunk or extremities, whereas a head and neck desmoid tumor is relatively rare.
Takuya Sawada, Masashi Mizumoto, Yoshiko Oshiro, Haruko Numajiri, Shosei Shimizu, Yuichi Hiroshima, Masatoshi Nakamura, Takashi Iizumi, Toshiyuki Okumura, Hideyuki Sakurai   +9 more
doaj   +1 more source

In the Beginning There Was Colectomy: Current Surgical Options in Familial Adenomatous Polyposis [PDF]

, 2004
Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1.
McGrath Daniel R, Spigelman Allan D
core   +2 more sources

Familial Adenomatous Polyposis—Risk of Cancer, Cancer Prevention, and Long‐Term Consequences: Learnings from Five Decades with the Danish Polyposis Register

APMIS, Volume 134, Issue 5, May 2026.
ABSTRACT Familial adenomatous polyposis (FAP) is a hereditary condition marked by the growth of hundreds to thousands of adenomatous polyps in the colon and rectum, significantly elevating the risk of colorectal cancer (CRC) if left untreated. Caused by pathogenic variants in the APC gene, FAP is typically identified in adolescence, often leading to ...
John Gásdal Karstensen
wiley   +1 more source

When is a GIST not a GIST? A case report of synchronous metastatic gastrointestinal stromal tumor and fibromatosis [PDF]

, 2009
Background A number of non-malignant diseases that share similar morphological features as gastrointestinal stromal tumor (GIST) have been reported. Co-existence of GIST with these other diseases is rarely recognized or reported.
Chee Khoon Lee, Alison Hadley, Keshani Desilva, Gareth Smith, David Goldstein, G Demetri, R Yantiss, H Ehrlich, A Al-Attar, J Desai, S Cheon, M Li, M Heinrich, J Mace, R Chugh, M Penel, J Jagadeesan, K Hobson, J Monihan, J Lee   +19 more
core   +4 more sources

A Case of Severe Acute Pancreatitis Following Endoscopic Biopsy of the Ampulla of Vater: A Rare Adverse Event of Esophagogastroduodenoscopy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Histological biopsy is essential for diagnosing ampullary tumors; however, it can occasionally result in severe adverse events. A 49‐year‐old male underwent esophagogastroduodenoscopic screening, which revealed an ampulla of Vater with enlargement of the oral protrusion.
Tetsushi Azami, Yuichi Takano, Go Akihiro, Mako Kitazono, Naoki Tamai, Jun Noda, Fumitaka Niiya, Kazuyuki Miyamoto, Masatsugu Nagahama   +8 more
wiley   +1 more source

Desmoid Tumor after Sleeve Gastrectomy: Case Report and Literature Review

GE: Portuguese Journal of Gastroenterology, 2023
Desmoid tumor is a rare mesenchymal neoplasm of unknown etiology. Despite rare, the diagnosis of desmoid tumors after bariatric surgery is increased over the last few years.
Renato Medas, Rosa Coelho, Renato Bessa-Melo, Pedro Pereira, Guilherme Macedo   +4 more
doaj   +1 more source