Results 81 to 90 of about 10,008 (224)

Expanding the Anatomical Distribution of PRRX1::KMT2D Fusion Mesenchymal Neoplasms: A Rare Mediastinal Case Report

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background PRRX1‐rearranged mesenchymal neoplasms are rare soft tissue tumors with a predilection for the superficial subcutaneous tissue. The PRRX1::KMT2D fusion variant is exceptionally rare, with only three previously reported cases, all of which were located in the intermuscular regions.
Weixiang Zhong, Yu Deng, Ke Sun
wiley   +1 more source

Fertility preservation in women with sarcoma: A real‐world experience

open access: yesInternational Journal of Cancer, Volume 158, Issue 5, Page 1178-1183, 1 March 2026.
What's New? Sarcomas frequently affect adolescent girls and young women, but limited data exist on ovarian function following sarcoma treatment. This observational cohort study evaluated the feasibility, timing, and clinical relevance of fertility preservation in young women treated for high‐grade sarcomas or desmoid tumors.
Guillaume Beinse   +11 more
wiley   +1 more source

Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors [PDF]

open access: yes, 2008
The heterogeneity that soft tissue sarcomas (STS) exhibit in their clinical behavior, even within histological subtypes, complicates patient care. Histological appearance is determined by gene expression.
Skubitz Amy PN   +3 more
core   +2 more sources

Bias and Fairness in Radiomics: A Comparative Analysis of Machine Learning Models on Four Oncology Datasets

open access: yesInternational Journal of Imaging Systems and Technology, Volume 36, Issue 2, March 2026.
ABSTRACT Radiomics, the practice of mining quantitative features from medical imaging, has gained increasing popularity in diagnosing and treating cancer. However, clinical deployment and adoption of radiomics tools in real‐world practice remain limited. To increase trust in radiomics models, one of the main remaining challenges is ensuring fairness by
Esmeralda Ruiz Pujadas   +5 more
wiley   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

open access: yesJournal of Surgical Oncology, Volume 133, Issue 4, Page 486-510, March 15, 2026.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado   +9 more
wiley   +1 more source

Our Experience with Desmoid Tumors

open access: yesTurkish Journal of Colorectal Disease, 2016
Aim: Desmoid tumors,which originate from musculoaponeurotic tissue, progress locally and agresively, but they do not make distant metastasis. Its frequency rises up with polyposis coli syndrome.
Metin Keskin   +5 more
doaj   +1 more source

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain   +5 more
wiley   +1 more source

Fibromatosis agresiva en hueco popliteo: A propósito de un caso [PDF]

open access: yes, 1999
Se presenta un caso de una masa indolora en región posterior de la pierna en un varón de 35 años de crecimiento rápido, consistencia firme y mal delimitada.
Cima Suárez, M. de   +2 more
core  

Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine [PDF]

open access: yes, 2009
Fibromatosis is a rare disease with benign histology. Its infiltrative growth pattern may prevent complete resection. We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway ...
Sze, H, Yeung, MW
core  

Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors

open access: yesPLoS ONE, 2022
Mutation in the CTNNB1 gene, leading to a deregulation of the WTN/β-catenin pathway, is a common feature of desmoid tumors (DTs). Many β-catenin inhibitors have recently been tested in clinical studies; however, BC2059 (also referred as Tegavivint), a ...
Danielle Almeida Braggio   +13 more
doaj  

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