Results 151 to 160 of about 11,754 (266)

Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin.

PLoS ONE, 2013
Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their plakin domains that provides divergent degrees
Caezar Al-Jassar, Pau Bernadό, Martyn Chidgey, Michael Overduin   +3 more
doaj   +1 more source

Spatial distribution of cell-cell and cell-ECM adhesions regulates force balance while main-taining E-cadherin molecular tension in cell pairs. [PDF]

, 2015
Mechanical linkage between cell-cell and cell-extracellular matrix (ECM) adhesions regulates cell shape changes during embryonic development and tissue homoeostasis.
Dunn, Alex R, Hart, Kevin C, Moeller, Jens, Nelson, W James, Pruitt, Beth L, Ramallo, Diego, Sim, Joo Yong, Vogel, Viola   +7 more
core   +1 more source

A case of arrhythmic cardiomyopathy caused by rare multiple gene mutations

Frontiers in Cardiovascular Medicine
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized by a high risk of ventricular tachycardia and sudden cardiac death, often involving the right ventricle or both ventricles, with the initial onset usually in adolescence or ...
Kaiqin Liang, Hong Wang, Minfang Wu, Meng Cui, Kaiyou Liu, Mintao Gan, Wengong Cheng, Aiqiong Huang   +7 more
doaj   +1 more source

Mechanical loading of desmosomes depends on the magnitude and orientation of external stress

Nature Communications, 2018
Desmosomes are intercellular adhesion complexes that connect the intermediate filament cytoskeletons of neighboring cells but direct evidence for their load-bearing nature is lacking.
Andrew J. Price, Anna-Lena Cost, Hanna Ungewiß, Jens Waschke, Alexander R. Dunn, Carsten Grashoff   +5 more
doaj   +1 more source

Expression of desmosomal proteins and their implications during enamel organ morphogenesis

Indian Journal of Dental Sciences, 2018
Background/Objective: The present article is between the fewest that describe the expression of desmosomal proteins in human tooth organ and to implicate desmosome and its components in tooth morphogenesis.
Hadi BILAL
doaj   +1 more source

Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. II. Morphological analysis. [PDF]

, 1988
Manijeh Pasdar, W. James Nelson
openalex   +1 more source

Isolation of cDNAs encoding desmosomal plaque proteins: evidence that bovine desmoplakins I and II are derived from two mRNAs and a single gene. [PDF]

, 1988
K J Green, Robert D. Goldman, Rex L. Chisholm   +2 more
openalex   +1 more source

Immunohistochemical localization and quantification of desmoplakins I & II and keratins 1 and 19 in plastic-embedded sections of human gingiva. [PDF]

, 1991
Robert P. Carmichael, C McCulloch, G A Zarb   +2 more
openalex   +1 more source

Loss‐of‐function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype

British Journal of Dermatology, 2019
Arrhythmogenic cardiomyopathy (AC) is an inherited, frequently underdiagnosed disorder, which can predispose individuals to sudden cardiac death. Rare, recessive forms of AC can be associated with woolly hair and palmoplantar keratoderma, but most ...
T. Maruthappu, A. Pósafalvi, Silvia Castelletti, P. Delaney, P. Syrris, Edel.A. O’Toole, Kathleen J. Green, Perry M. Elliott, PD Lambiase, PD Lambiase, Andrew Tinker, William J. McKenna, D. Kelsell   +12 more
semanticscholar   +1 more source

Data from Palmitate-Induced IRE1–XBP1–ZEB Signaling Represses Desmoplakin Expression and Promotes Cancer Cell Migration [PDF]

, 2023
Aritro Nath, Amrita Oak, Kevin Y. Chen, Irene Li, R. Chauncey Splichal, Jason Portis, Sean Foster, S. Patrick Walton, Christina Chan   +8 more
openalex   +2 more sources