Results 131 to 140 of about 396,082 (288)
Threonine 348 regulates the subcellular localization of PTEN
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Covers OCLC #1402231873, OCLC #914812545, OCLC #1057124055, OCLC #1402231887Survey conducted by Longwoods International, -2017; Destination Analysts, 2021/2022-This archived document is maintained by the State Library of Oregon as part of the Oregon ...
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Tourscape, cultural identity, and loyalty in a themed cultural precinct: A study of Datang Everbright City in Xi'an, China. [PDF]
Nie G, Li P, Yan M, Ai S, He J.
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Prediction Model for Discharge Destination in Older Patients After Hip Fracture Surgery Using Early Predictors. [PDF]
Krakers SM +4 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
From destination perceptions to visit behavior in Macao: a sequential mediation model of motivation, attitude, and intention among Mainland Chinese tourists. [PDF]
Yang F, Jiang S.
europepmc +1 more source

