Results 51 to 60 of about 396,083 (241)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Luxury consumption in tourism: the case of Dubai – Part 2

open access: yesResearch in Hospitality Management, 2020
2016 was a year of critical discussion and reflection for Nadkarni and Heyes as they considered the luxury image of Dubai in this journal. Discussions outlined the theoretical nature of luxury while also addressing the current hotel industry statistics ...
Andy Heyes, Sanjay Nadkarni
doaj   +1 more source

Transport and infrastructural basis of the tourism development strategy in the Arkhangelsk Oblast

open access: yesАрктика и Север, 2020
The article, devoted to the analysis of transport and geographical locations, describes possible strategies for the development of tourism in the Arkhangelsk Oblast.
TSVETKOV A.Yu.
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Interaction and Conditionality of Hotel Business and Maritime Tourism, as a Significant Factor in Increasing Revenues in Tourism

open access: yesECONOMICS, 2019
The manner how to increase the revenues in tourism, is the question that can be answerd on different ways. One of the ways that may contribute that is the interaction and conditionality of hotel business and maritime tourism.
Kaluđerović Marija
doaj   +1 more source

Innovations événementielles et structuration des destinations touristiques. Pour une hybridation des approches : l’exemple de l’Ultra-Trail du Mont-Blanc

open access: yesMondes du Tourisme, 2016
In the current context of reconfiguration and increased competition between regions, many destinations are attempting to stand out by organizing high-profile events whose objective is to enhance their region’s reputation. From an analytical point of view,
Olivier Bessy
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Unmanageable Tourism Destination Brands? [PDF]

open access: yes
Increasingly researchers and practitioners adopt branding to build and manage tourism destination images. However, we have yet to ask the question: Is it pos-sible to build and/or manage destination brands? This crucial question is ad-dressed by means of:
Bodil Stilling Blichfeldt
core  

The relationship between tourist satisfaction and posttravel behaviour: Evidence from international tourists visiting Ethiopia [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
The satisfactions and memorable experience of visitors is a result of both quality service and unique destination attributes. The aim of this research was to study the relationship between tourist satisfaction and post travel behaviour.
Kassegn Berhanu, Prof. Dr. Sahil Raj
doaj  

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