Results 61 to 70 of about 395,567 (287)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The manner how to increase the revenues in tourism, is the question that can be answerd on different ways. One of the ways that may contribute that is the interaction and conditionality of hotel business and maritime tourism.
Kaluđerović Marija
doaj +1 more source
In the current context of reconfiguration and increased competition between regions, many destinations are attempting to stand out by organizing high-profile events whose objective is to enhance their region’s reputation. From an analytical point of view,
Olivier Bessy
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Generally speaking, destination choice represents an optimization problem, where every agent searches for his or her optimal destination according to an objective function, subject to various constraints such as the agent’s travel time budget – as well as interactions with other agents – while competing for space-time slots in the infrastructure.
Horni, Andreas +2 more
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Unmanageable Tourism Destination Brands? [PDF]
Increasingly researchers and practitioners adopt branding to build and manage tourism destination images. However, we have yet to ask the question: Is it pos-sible to build and/or manage destination brands? This crucial question is ad-dressed by means of:
Bodil Stilling Blichfeldt
core
The relationship between tourist satisfaction and posttravel behaviour: Evidence from international tourists visiting Ethiopia [PDF]
The satisfactions and memorable experience of visitors is a result of both quality service and unique destination attributes. The aim of this research was to study the relationship between tourist satisfaction and post travel behaviour.
Kassegn Berhanu, Prof. Dr. Sahil Raj
doaj
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
City break as a form of urban tourism
The aim of this paper is to investigate the attractiveness of city break trips as a form of urban (cognitive) tourism. The study focuses on the following research questions: What factors influence the popularity of city break trips? Which cities are most
Agata Balińska
doaj +1 more source

