Results 51 to 60 of about 483,601 (346)

Tourism development techniques in the urban master plan

open access: yesCogent Business & Management, 2022
This paper analyzes planning and design techniques of tourism complexes in the process of municipalities’ master planning. First, it explains the importance of the tourism industry with the help of the theories of scholars and experts.
Abdol Aziz Shahraki
doaj   +1 more source

Impacts of COVID-19 on tourists' destination preferences: Evidence from China

open access: yesAnnals of Tourism Research, 2021
Using data of online ticket sales for attractions in the seven provinces of South Central China, this study focuses on the impact of COVID-19 on tourists' destination preferences after the end of lockdown.
Xun Li   +3 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Re-modelling Muslim-friendly tourism value chain ecosystem: the case study of West Sumatera, Indonesia

open access: yesCogent Social Sciences
The development of Muslim-friendly tourism destinations is an effort to differentiate products and the tourism market amidst the aggressive growth of global tourism.
Anang Sutono   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Is online learning effective for practice-based tourism courses? A constructive learning approach

open access: yesTourism and Hospitality Management
Purpose – The aim of this paper is to 1) measure the effectiveness of online learning in practise-based tourism courses, 2) identify the factors that influence the effectiveness of online learning and 3) propose strategies to encourage tourism students
Ilham Junaid, Marianna Sigala
doaj   +1 more source

The impact of climate change on visitor destination selection: A case study of the Central Drakensberg Region in KwaZulu-Natal

open access: yesJàmbá, 2021
Many variables influence visitors’ destination choices, for example, affordability, attractions, health and safety, and expectancies. Amongst the indirect influences in destination choice by tourists, climate change is perhaps the greatest factor because
Nduduzo A. Ngxongo
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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