Results 31 to 40 of about 396,083 (241)
Turizmde Yeni Ürün Geliştirme ve Pazarlama Stratejileri: Kastamonu Şehir Merkezi Destinasyonu Örneği
Amaç: Turizmden sağlanan gelirlerin kalkınmaya önemli katkılarının olduğu bilinmektedir. Bu katkılarından dolayı turistik destinasyonlar arasındaki rekabet hızla artmaktadır.
Nagehan Büyükmehmetoğlu, Kutay Oktay
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Background: The sequence effect (SE), referring to step-to-step reduction in amplitude, is considered to lead to freezing of gait (FOG) in Parkinson's disease (PD). Visual cues may alleviate SE and help reduce freezing episodes.
Shan-Shan Cao +4 more
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This paper aims to conceptually develop a business model typology in tourism. It focuses on digitalization and destination location as important contextual factors when developing the typology.
Gabriel Linton, Christina Öberg
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Beyond Tourism: The Ways of Salatiga Culinary Business People to Survive Covid-19
During the COVID-19 pandemic, the sustainability of tourism-related livelihoods was significantly impacted. Tourism-related SMEs, including culinary businesses, have strived to find ways to endure the pandemic.
Rio Giovano Setiawan +1 more
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Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Will Generation Z Use ChatGPT for Tourism Recommendations?
Purpose – This research note examines Generation Z’s acceptance of ChatGPT as a Tourism Recommender System, to better understand whether they will use it for a tourism recommendation, and the factors influencing their acceptance.
Anom Hery SUASAPHA
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