Results 211 to 220 of about 120,649 (286)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Qatar's FIFA World Cup odyssey: A quest for legacy transforming a small nation into a global destination. [PDF]

Heliyon
Hajjaj M, Borodin V, Perțicas DC, Florea AG.   +3 more
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Perceived differences in coastal tourism image under tourist experience-IPA analysis based on UGC data of 12 coastal cities. [PDF]

PLoS One
Zhang M, Di Q, Liu Y.
europepmc   +1 more source

Design of a Cobalt‐Free Maraging Steel with Ultra‐High Strength of 2.3 GPa Through Additive Manufacturing

Advanced Science, EarlyView.
A computationally designed, cobalt‐free maraging steel tailored for additive manufacturing achieves an ultra‐high tensile strength of 2.3 GPa with 5.7% elongation. This exceptional strength‐ductility synergy stems from high‐density core‐shell Ni3Ti/NiAl nanoprecipitates, a crack‐resistant composition, and a fine equiaxed grain structure enabled by ...
Hu Li, Shubo Gao, Liming Tan, Weiming Ji, Liuliu Han, Kun Zhou, Yong Liu   +6 more
wiley   +1 more source

Will tourism cultural experience affect tourist citizenship behaviors? A case of the "Village Basketball League" in Taijiang County, Guizhou Province. [PDF]

PLoS One
Yang Y, Lin Y, Qiu C, Chen Y, Fan S, Chen Z, Ma Y.   +6 more
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Different paths, same destination, yet diverse effects: Antecedent configurations and performance implications of digital transformation in pharmaceutical manufacturing enterprises--Evidence from Chinese listed companies. [PDF]

PLoS One
Shi B, Mou C, Zhang Y, Cui T.
europepmc   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Verification of the Impact of Sports Event Service Quality and Host Destination Image on Sports Tourists' Behavioral Intentions Through Meta-Analytic Structural Equation Modeling. [PDF]

Behav Sci (Basel)
Jia H, Kim D, Kim K.
europepmc   +1 more source