Results 41 to 50 of about 120,649 (286)
Application of tourism destination competitiveness model on rural destinations
Journal of the Geographical Institute Jovan Cvijic, SASA, 2017 Measuring competitiveness has become one of the key factors for ensuring successful and sustainable tourism development, especially destination's current level of development and its growth and vitality. The main goal of this study was to analyze the applicability of the Ritchie and Crouch competitiveness model in order to assess tourism advantages and
Dunja Demirović +4 more
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Stakeholders Perspective on Competitiveness and Sustainability of Farm Destinations
International Journal of Academe and Industry Research, 2021 Farm tourism is becoming one of the Philippines’ most profitable businesses. The potential of farms has prompted the formation of farm destinations in the province of Cavite.
Hermilina A. Mendoza
doaj +1 more source
A Dimensional Framework of Tourism Indicators Influencing Destination Competitiveness [PDF]
African Journal of Hospitality, Tourism and Leisure, 2020 The tourism industry has become more competitive with recent developments in information technology. This has assisted tourists to select the best tourist destination, often those providing the highest standard of services within a reasonable price ...
Danie Ferreira, Sandra Perks
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
National and urban public policy agenda in tourism. Towards the emergence of a hyperneoliberal script? [PDF]
, 2017 Following the 2007–2009 Global Financial Crisis (GFC), some national governments have been pursuing a counter-reform of the public sector characterised by further policy centralisation and the ‘hollowing out’ of regional authorities.
Amore, Alberto, Hall, Colin Michael
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Consumer Protection as a Factor of Destination Competitiveness in the European Union [PDF]
Amfiteatru Economic, 2017 Many tourism destinations have enacted and implemented laws to protect residents as consumers that are relevance to tourists as consumers. In literature, consumer protection is not explicitly considered and analyzed in the area of destination ...
Jelena Petrović , Snežana Milićević
doaj
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source