Results 101 to 110 of about 4,854,757 (315)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Tranexamic acid increases early perioperative functional outcomes after total knee arthroplasty
Arthroplasty Today, 2018 Background: The purpose of this study was to investigate the influence of tranexamic acid (TXA) on functional outcomes in the immediate postoperative period after total knee arthroplasty (TKA).
Matthew J. Grosso, MD +6 more
doaj +1 more source
Role of Palliative Care in Patients with Destination Therapy Left Ventricular Assist Device [PDF]
, 2017 Lavanya Bellumkonda
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Left ventricular assist device as destination therapy: Application of the payment-by-results approach for the device reimbursement [PDF]
, 2009 Andrea Messori +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure
Case Reports in Infectious Diseases, 2019 Left ventricular assisted devices (LVADs) have revolutionized the treatment of advanced heart failure, providing meaningful increases in survival, functional capacity, and quality of life.
David R. Murillo-Garcia +7 more
doaj +1 more source
Total Artificial Heart as the Destination Therapy: A Review
, 2017 Introduction: For the patients awaiting cardiac transplantation, mechanical circulatory support has been widely utilized in the form of left ventricular assist device or total artificial heart.
A. M. Minhas +6 more
semanticscholar +1 more source
A Case of Destination Therapy for Dilated Cardiomyopathy with Ventricular Assisted Device [PDF]
, 2015 Kanna Fujita +4 more
openalex +1 more source