Sex Differences in Recovery and Device Replacement After Left Ventricular Assist Device Implantation as Destination Therapy [PDF]
Background The relevance of sex and preimplant factors for clinical outcomes among patients with left ventricular assist devices intended for destination therapy is unclear.
Lisa‐Marie Maukel +3 more
doaj +5 more sources
Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right [PDF]
For almost half a century, cardiac transplant has been the only long-term treatment for patients with end-stage heart failure. Implantable left ventricular assist devices (LVADs) have emerged as a new treatment option for advanced heart failure as ...
Antoni Bayes-Genis +7 more
doaj +5 more sources
Left Ventricular Assist Device as a Destination Therapy: Current Situation and the Importance of Patient Selection [PDF]
Advanced heart failure is a growing problem for which the best treatment is cardiac transplantation. However, the shortage of donors’ hearts made left ventricular assist devices as destination therapy (DT-LVAD) a highly recommended alternative: they ...
María Melendo-Viu +11 more
doaj +3 more sources
Perceptions of Bereaved Caregivers and Clinicians About End‐of‐Life Care for Patients With Destination Therapy Left Ventricular Assist Devices [PDF]
Background Patients with left ventricular assist devices (LVADs) implanted as destination therapy may receive suboptimal preparation for and care at the end of life, but there is limited understanding of the reasons for these shortcomings.
Sarah Chuzi +5 more
doaj +3 more sources
Time in Therapeutic Range Significantly Impacts Survival and Adverse Events in Destination Therapy Patients. [PDF]
Supplemental Digital Content is available in the text. The study aim was to examine the impact time in therapeutic range (TTR, International Normalized Ratio [INR] 2.0–3.0) has on survival and adverse events in patients receiving the HeartWare HVAD ...
Macaluso GP +8 more
europepmc +3 more sources
Cost-effectiveness of Left Ventricular Assist Devices (LVADs) as destination therapy in the UK: An economic modelling study. [PDF]
ObjectivesLeft Ventricular Assist Devices (LVADs) for destination therapy (DT) are used in many countries but in some, like the UK, LVADs are not commissioned due to uncertainty around their cost-effectiveness.
Tuba Saygın Avşar +7 more
doaj +3 more sources
Heart failure in Poland: Left ventricular assist device destination therapy and other challenges of interventional cardiology and cardiac surgery [PDF]
Patients with severe heart failure (HF), who are not eligible for cardiac transplantation and receive optimal medical management, based mainly on the use of pharmacological treatment and devices such as resynchronization therapy (implantable cardioverter-
Mariusz Kuśmierczyk +19 more
doaj +3 more sources
Cost‐effectiveness of left ventricular assist devices as destination therapy in the United Kingdom [PDF]
Aims Continuous‐flow left ventricular assist devices (LVADs) as destination therapy (DT) are a recommended treatment by National Institute for Health and Care Excellence England for end‐stage heart failure patients ineligible for cardiac transplantation.
Stephan Schueler +10 more
doaj +3 more sources
Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient-a case report. [PDF]
Background Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be ...
Koppel CJ +3 more
europepmc +4 more sources
Mechanical circulatory support for destination therapy [PDF]
Patients with chronic heart failure who are not eligible for heart transplant and whose life expectancy depends mainly on the heart disease may benefit from mechanical circulatory support. Mechanical circulatory support restores adequate cardiac output and organ perfusion and eventually improves patients' clinical condition, quality of life and life ...
Piergiorgio Tozzi, Roger Hullin
doaj +6 more sources

