Key Points Question In patients with advanced heart failure, do outcomes with left ventricular assist device implantation differ by the initial intended goal of therapy as a bridge to transplant or destination therapy?
Goldstein DJ +18 more
europepmc +2 more sources
Left ventricular assist device implantation in high risk destination therapy patients: an alternative surgical approach [PDF]
Left Ventricular Assist Device (LVAD) for Destination Therapy (DT) is an established therapy for end stage heart failure patients who are not transplant candidates.
Samuels Louis E +3 more
doaj +2 more sources
Importance Shared decision making helps patients and clinicians elect therapies aligned with patients’ values and preferences. This is particularly important for invasive therapies with considerable trade-offs.
Allen LA +15 more
europepmc +2 more sources
Driveline Infection in Ventricular Assist Devices and Its Implication in the Present Era of Destination Therapy. [PDF]
Advances in mechanical circulatory support devices provided the technology to develop long-term, implantable left ventricular assist devices as bridge to transplant, destination therapy, and in a lesser group of patients, as bridge to recovery.
Hernandez GA, Breton JDN, Chaparro SV.
europepmc +2 more sources
Heart transplantation versus left ventricular assist devices as destination therapy or bridge to transplantation for 1-year mortality: a systematic review and meta-analysis. [PDF]
Background The optimal treatment for advanced heart failure (HF) patients with regards to mortality remains unknown. Heart transplantation (HTx) and left ventricular assist devices (LVAD) used either as a bridge to transplant (BTT) or destination therapy
Theochari CA +6 more
europepmc +2 more sources
Destination Therapy Strategies of Advanced Heart Failure in Elderly Non-Heart Transplant Candidates: A Propensity Matching Analysis from the LEVO-D and REGALAD Registries [PDF]
Heart transplantation (HT) is the gold standard therapy for advanced heart failure (ADHF), and LVADs as destination therapy are an option in non-HT candidates.
David Dobarro +33 more
doaj +2 more sources
An infectious disease perspective-is destination therapy a viable option for total artificial hearts? [PDF]
Zabner R, Lam LD, Runyan C.
europepmc +3 more sources
Mechanical circulatory support for destination therapy: why are we so late? [PDF]
Robert Guidoin
doaj +2 more sources
Social Determinants of Health and Rates of Implantation for Patients Considering Destination Therapy Left Ventricular Assist Device. [PDF]
Flint K +9 more
europepmc +2 more sources

