Results 51 to 60 of about 693 (168)

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Well‐being on supportive techniques in amyotrophic lateral sclerosis: from neurologists' perspective

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1874-1883, December 2022., 2022
Abstract Objective To investigate intercultural neurologists' perception of well‐being in patients with amyotrophic lateral sclerosis (ALS) using gastrostomy (PEG), non‐invasive, and/or invasive ventilation (NIV/IV) and to analyse the determinants and impact on the management of the above medical interventions (MIs).
Krzysztof Barć, Dorothée Lulé, Julia Finsel, Olga Helczyk, Susanne Baader, Helena Aho‐Özhan, Albert C. Ludolph, Magdalena Kuźma‐Kozakiewicz   +7 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Perspectives from mechanical circulatory support coordinators on the pre-implantation decision process for destination therapy left ventricular assist devices [PDF]

, 2015
Colleen K. McIlvennan, Daniel D. Matlock, Madhav Narayan, Carolyn T. Nowels, Jocelyn S. Thompson, Anne Cannon, William John Bradley, Larry A. Allen   +7 more
openalex   +1 more source

重症心不全に対する機械的循環補助の進歩 : Bridge to TransplantationからDestination Therapyまで(<特集II>第66回日本循環器学会学術集会)

, 2003
甲元 拓志, 中 好文
openalex   +2 more sources

Destination Therapy in a Single European Country. Insights from the ITAMACS Registry [PDF]

, 2016
G. Feltrin, Federico Pappalardo, Gino Gerosa, Claudio Russo, Mauro Rinaldi, Massimo Maccherini, Anna Apostolo, Giuseppe Faggian, Ugolino Livi, Attilio Iacovoni, Massimo Massetti, Francesco Musumeci, Gabriele Di Giammarco, Giuseppe Ambrosio, Antonio Loforte, Daniela Pini, Calogero Falletta, Cristiano Amarelli, A Grimaldi, Francesco Pagani, Giuseppe Leonardi, A. Frigo, L. Rizzato, Alessandro Nanni Costa   +23 more
openalex   +1 more source

Frequency of Poor Outcome (Death or Poor Quality of Life) After Left Ventricular Assist Device for Destination Therapy [PDF]

, 2016
Suzanne V. Arnold, Philip G. Jones, Larry A. Allen, David J. Cohen, Timothy J. Fendler, Jonathan E. Holtz, Sanjeev Aggarwal, John A. Spertus   +7 more
openalex   +1 more source

LONG-TERM, IN VITRO RELIABILITY TESTING FOR LVADS INTENDED FOR DESTINATION THERAPY

, 2004
Kevin Bourque, Charles Dague, Howard M. Loree, A Flieschli, T Gempp, A Siebenhaar, V Steinacher, R Schoeb, David J. Farrar, V. Poirier   +9 more
openalex   +1 more source

Enhanced dose prediction for head and neck cancer artificial intelligence‐driven radiotherapy based on transfer learning with limited training data

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Training deep learning dose prediction models for the latest cutting‐edge radiotherapy techniques, such as AI‐based nodal radiotherapy (AINRT) and Daily Adaptive AI‐based nodal radiotherapy (DA‐AINRT), is challenging due to limited data.
Hui‐Ju Wang, Austen Maniscalco, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +5 more
wiley   +1 more source