Results 51 to 60 of about 109,033 (289)

A Peek at LVADs Pumping to Recovery

Clinical Medicine Insights: Cardiology, 2022
Left ventricular assist devices (LVADs) have revolutionized the management of patients with advanced heart failure refractory to medical therapy. Current indications of LVADs include Bridge to Transplantation (BTT), Destination Therapy (DT) for long-term
Samiullah Arshad, Rachel D Cutting, Daniel J Stephens, Ythan H Goldberg, Claudius Mahr, Mahender Vyasabattu, Ahmed H Abdelfattah, Gaurang N Vaidya   +7 more
doaj   +1 more source

Acute ST-elevation myocardial infarction with Guillain-Barre syndrome in Fontan circulation

Annals of Pediatric Cardiology, 2023
Total cavopulmonary connection, commonly referred to as the Fontan procedure, is the established destination therapy for univentricular hearts. While the procedure permits a longer survival of these patients, this circulation involves several compromises
Rohit Sunil Walse, Bhagwati Pant, Arun Gopalakrishnan, Bijulal Sasidharan   +3 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Travelers’ diarrhea and other gastrointestinal symptoms among Boston-area international travelers [PDF]

, 2017
INTRODUCTION: Travelers' diarrhea (TD) and non-TD gastrointestinal (GI) symptoms are common among international travelers. In a study of short-term travelers from Switzerland to developing countries, the most common symptom experienced was severe ...
Barnett, Elizabeth D., Benoit, Christine M., Chen, Lin H., Hamer, Davidson H., Han, Pauline V., Jentes, Emily S., NacLeod, William B., Stoney, Rhett J., Wilson, Mary E.   +8 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Longest Known Survivor With HeartMate II Continuous‐Flow Left Ventricular Assist System—A Case Report of the 16‐Year Success Story

Clinical Case Reports
Left ventricular assist devices (LVADs) have been used as a bridge to transplantation in patients with advanced heart failure. In this case, LVAD therapy was used as a destination therapy for 16 years, representing the longest documented and continuously
Yamane Chawa, Mhd Baraa Habib, Ammar Chapra, Salah Elbdri   +3 more
doaj   +1 more source

Improving the perceived contribution of sustainable tourism through the residents’ empowerment and support for tourism development: A different age group context [PDF]

Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu
This study aims to investigate the relationships of the residents’ empowerment and support for tourism development with the perceived contribution of sustainable tourism and to identify precise attributes among different resident age groups, which can be
Lorena Bašan, Ivana Perušina, Marija Ham   +2 more
doaj   +1 more source