Results 51 to 60 of about 4,854,757 (315)

End-of-life discontinuation of destination therapy with cardiac and ventilatory support medical devices: physician-assisted death or allowing the patient to die?

BMC Medical Ethics, 2010
Background Bioethics and law distinguish between the practices of "physician-assisted death" and "allowing the patient to die." Discussion Advances in biotechnology have allowed medical devices to be used as destination therapy that are designed for the ...
Rady Mohamed Y, Verheijde Joseph L
doaj   +1 more source

Heart failure risk scores in advanced heart failure patients: insights from the LEVO‐D registry

ESC Heart Failure, 2023
Aims The prevalence of advanced heart failure (HF) is increasing due to the growing number of patients with HF and their better treatment and survival.
Pau Codina, David Dobarro, Javier deJuan‐Bagudá, Fernando De Frutos, Josep Lupón, Antoni Bayes‐Genis, José Gonzalez‐Costello, Spanish LEVO‐D registry Collaborators   +7 more
doaj   +1 more source

Mechanical Ventricular Assistance as Destination Therapy for End-Stage Heart Failure: Has it become a first line therapy?

Frontiers in Surgery, 2015
Patients with end-stage heart failure have poor quality of life and prognosis.Therapeutic options are scarce and not available for all:only few patients can be transplanted and several medical and surgical strategies have shown limited ability to ...
Massimo eBonacchi, Guy eHarmelin, Marco eBugetti, Guido eSani   +3 more
doaj   +1 more source

A Peek at LVADs Pumping to Recovery

Clinical Medicine Insights: Cardiology, 2022
Left ventricular assist devices (LVADs) have revolutionized the management of patients with advanced heart failure refractory to medical therapy. Current indications of LVADs include Bridge to Transplantation (BTT), Destination Therapy (DT) for long-term
Samiullah Arshad, Rachel D Cutting, Daniel J Stephens, Ythan H Goldberg, Claudius Mahr, Mahender Vyasabattu, Ahmed H Abdelfattah, Gaurang N Vaidya   +7 more
doaj   +1 more source

Ethical challenges with the left ventricular assist device as a destination therapy

Philosophy, Ethics, and Humanities in Medicine, 2008
The left ventricular assist device was originally designed to be surgically implanted as a bridge to transplantation for patients with chronic end-stage heart failure.
Rady Mohamed Y, Verheijde Joseph L, Rizzieri Aaron G, McGregor Joan L   +3 more
doaj   +1 more source

Acute ST-elevation myocardial infarction with Guillain-Barre syndrome in Fontan circulation

Annals of Pediatric Cardiology, 2023
Total cavopulmonary connection, commonly referred to as the Fontan procedure, is the established destination therapy for univentricular hearts. While the procedure permits a longer survival of these patients, this circulation involves several compromises
Rohit Sunil Walse, Bhagwati Pant, Arun Gopalakrishnan, Bijulal Sasidharan   +3 more
doaj   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source