Results 121 to 130 of about 155 (155)

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

Small, EarlyView.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang, Yilin Yang, Nicole Henry, Boram Gu, Jiahua Wang, Yuanyuan Guo, Colin Longstaff, Simon A. Thom, Yuehua Li, Xiao Yun Xu, Rongjun Chen   +10 more
wiley   +1 more source

Self‐Driven Hybrid Piezomagnetic–Iontronic Mechanoreceptors for Bimodal SA/RA Perception and Tactile Synthesis

Small, EarlyView.
A bimodal mechanoreceptor, integrating a piezomagnetic elastomer and an ion gel, simultaneously and independently transduces external mechanical stimuli into independent slow‐adapting signals for static pressure and rapid‐adapting signals for dynamic vibration.
Kyoung‐Yong Chun, Sang‐Hyun Lee, Joongmi Kim, Chang‐Soo Han   +3 more
wiley   +1 more source

A Retinomorphic Graphene Transistor Implementing Direction‐ and Velocity‐Selective Computation for In‐Sensor Image Stabilization

Small, EarlyView.
A multi‐gated ion‐gel graphene transistor architecture emulates spatiotemporal dendritic filtering inspired by biological direction‐selective retinal circuits. Leveraging distributed resistance‐capacitive ionic relaxation delays under combined excitation‐inhibition pulse routines, the solid‐state device exhibits programmable direction‐selective index ...
Jun Ha Park, HoYeon Kim, Jinkyung Kim, Hyun Jae Jang, Jae Wook Kim, Jongkil Park, Seongsik Park, Inho Kim, Suyoun Lee, Gyu Weon Hwang, Byeong‐Kwon Ju, Kyeong‐Seok Lee   +11 more
wiley   +1 more source

Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating

Small, EarlyView.
Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim, Lingqing Zong, Wei Deng, Maria Kavallaris, Zi Gu   +4 more
wiley   +1 more source

A lysosomal escape‐enabled endoplasmic reticulum‐targeting BODIPY photothermal agent for enhanced tumor ablation

Smart Molecules, EarlyView.
To advance precision cancer therapy, we engineered ER‐BDP NPs, a self‐assembled nanomedicine designed for selective ER localization. By integrating organelle targeting with localized laser activation, this agent mediates precision‐guided tumor destruction in vitro and in vivo while reducing off‐target effects, effectively balancing therapeutic efficacy
Shaoyang Shi, Yanbing Cao, Jiexuan Zuo, Qiushi Li, Xiaolong Zeng, Jianjun Du, Jiangli Fan, Wen Sun, Xiaojun Peng   +8 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Investigating the Iron‐Steam Process for Coupling With SOEC and SOFC: A Step Toward Integrated Hydrogen and Electricity Storage

steel research international, EarlyView.
Fixed‐bed reactor experiments (10 L) validate the iron–steam redox process, bridging material‐scale research and industrial power‐to‐power applications. Coupled with SOEC/SOFC systems, this framework defines critical interfaces for heat and gas management. Results confirm reproducible hydrogen storage and release, demonstrating technical feasibility at
Julien Göthel, Radek Vostal, Olena Volkova   +2 more
wiley   +1 more source

Vision language models for bridge inspections: A review of applications in image‐based damage documentation

Structural Concrete, EarlyView.
Abstract Automating bridge inspections requires more than detecting individual damage instances. It demands systems capable of describing, contextualizing, and interpreting damage in an inspection‐relevant manner. Conventional computer vision approaches, such as object detection and segmentation, primarily address visual recognition tasks and are ...
Rona Firdes Çelik, Ulas Bagci, Sylvia Kessler   +2 more
wiley   +1 more source

Deflection‐based assessment of residual prestress in simply‐supported bridges accounting for creep variability

Structural Concrete, EarlyView.
Abstract Several test methods have been proposed in the literature for measuring the level of residual prestress, most of them involving either semi‐ or fully destructive techniques for local measurements which could be highly sensitive to boundary conditions and execution details.
Giuseppe Zarrella, Daniele Losanno, Alfred Strauss   +2 more
wiley   +1 more source

Multi‐Vine Disease Prediction in a Field Test Spanning Whole Growth Season at Wine‐Industrial Site (McLaren Vale)

Artificial Intelligence for Engineering, EarlyView.
Overall, the findings provide reliable evidence for block‐level disease early warning, inspection prioritisation, and spray decision‐making, helping to reduce unnecessary inputs, lower environmental burdens, and improve the resilience and sustainability of vineyard production systems.
Shu Liang, Nguyen Van Duc Long, Mst Irin Parvin, Philip Kwong, Vinay Pagay, Maria Maglieri, Steve Maglieri, Andrew Godfrey, Harpinder Sandhu, Kartheek Munigoti, Nicola Sasanelli, Pieter van Schalkwyk, Freya Richardson, Bhola Paudel, Pramod Gautam, Kashif Khaqan, Volker Hessel   +16 more
wiley   +1 more source