Results 151 to 160 of about 7,489,623 (289)

Disentangling the Determinants of Successful Demobilization and Reintegration [PDF]

Since 1989, international efforts to end protracted conflicts in Africa, Latin America, and Asia have included sustained investments in the disarmament, demobilization, and reintegration (DDR) of combatants from the warring parties.
Jeremy Weinstein, Macartan Humphreys
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dual-resolution megahertz optical coherence tomography prototype rectoscope for enhanced visualization of colorectal microstructures. [PDF]

J Biomed Opt
Burhan S, Schulte B, Göb M, Singh AP, Mustafa B, Lotz S, Draxinger W, Lamminger P, Saker Y, Eixmann T, Ahrens M, Heimke M, Heinze T, Wedel T, Rahlves M, Ellrichmann M, Huber R.   +16 more
europepmc   +1 more source

How to Do xtabond2: An Introduction to "Difference" and "System" GMM in Stata [PDF]

The Arellano-Bond (1991) and Arellano-Bover (1995)/Blundell-Bond (1998) linear generalized method of moments (GMM) estimators are increasingly popular. Both are general estimators designed for situations with "small T, large N" panels, meaning few time ...
David Roodman
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

How do clinician and parent-reported data differ? An analysis of similarity and difference in the datasets from a cross-syndrome genetics cohort study (GenROC). [PDF]

J Med Genet
Low KJ, Day H, Thanthilla MLK, GenROC consortium, Davis C, Firth HV, Wright C, GenROC consortium.   +7 more
europepmc   +1 more source

Will Debt Relief Make a Difference? Impact and Expectations of the Multilateral Debt Relief Initiative [PDF]

The Multilateral Debt Relief Initiative (MDRI) is the latest phase of debt reduction for poor countries from the World Bank, the IMF, and the African Development Bank. The MDRI, which will come close to full debt reduction for at least 19 (and perhaps as
Todd Moss
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Novelties in <i>Uvaria</i> (Annonaceae) from West Africa. [PDF]

PhytoKeys
Jongkind CCH.
europepmc   +1 more source

Ten Myths of the International Finance Facility [PDF]

The British proposal to create an International Finance Facility in order to ‘frontload’ $50 billion in aid per year until 2015 has generated a lot of attention and will likely be a major topic at the G8 meeting this July.
Todd Moss
core   +1 more source