Results 81 to 90 of about 7,489,623 (289)

Can Global De-Carbonization Inhibit Developing-Country Industrialization? [PDF]

open access: yes
Most economic analyses of climate change have focused on the aggregate impact on countries of mitigation actions. We depart first in disaggregating the impact by sector, focusing particularly on manufacturing output and exports because of the potential ...
Aaditya Mattoo   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Fresh Look at Global Governance: Exploring Objective Criteria for Representation [PDF]

open access: yes
The geopolitical world of the 21st century is very different than that of the post– World War II era. In this new world order, what constitutes a system of global governance?
Enrique Rueda-Sabater   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Clinical and laboratory characteristics of patients hospitalized with severe COVID-19 in New Orleans, August 2020 to September 2021

open access: yesScientific Reports
Louisiana experienced high morbidity and mortality from COVID-19. To assess possible explanatory factors, we conducted a cohort study (ClinSeqSer) of patients hospitalized with COVID-19 in New Orleans during August 2020–September 2021.
Arnaud Drouin   +12 more
doaj   +1 more source

Behavioral Foundations of Democracy and Development [PDF]

open access: yes
Since 1974 the world has experienced a “third wave” of democratization. Ensuring that these new democracies consolidate is critical to both global prosperity and peace.
Ethan Kapstein
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

New Data, New Doubts: Revisiting "Aid, Policies, and Growth" [PDF]

open access: yes
The Burnside and Dollar (2000) finding that aid raises growth in a good policy environment has had an important influence on policy and academic debates.
David Roodman   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Raumkategorien. Breslauer Architektur der ersten Hälfte des 20. Jahrhunderts als Träger visueller Information

open access: yesLinguistische Treffen in Wrocław, 2019
In meinem Beitrag möchte ich eine Überlegung über Platz und Bedeutung der Rhetorik als Werkzeug visueller Information in Anlehnung an die Proxemik-Theorie anstellen – einer Wissenschaft, die den Einfluss der räumlichen Verhältnisse auf den Menschen ...
Agata Gwizd-Leszczyńska
doaj   +1 more source

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