Results 111 to 120 of about 1,357,733 (304)

Optimised surface-electrode ion-trap junctions for experiments with cold molecular ions

open access: yes, 2017
We discuss the design and optimisation of two types of junctions between surface-electrode radiofrequency ion-trap arrays that enable the integration of experiments with sympathetically cooled molecular ions on a monolithic chip device.
Mokhberi, Arezoo   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Input and output considerations in estimating rates of chemical denudation [PDF]

open access: yes, 1970
Estimation of rates of solutional denudation in river basins necessitates some consideration of salt inputs as well as consideration of salt outputs.
Goudie, Andrew
core   +1 more source

Thematic workshop: spices, the chemistry in small details

open access: yes, 2020
The present work is an excerpt from a dissertation that defends the use of means of scientific dissemination in a formal teaching context. The research is of a qualitative nature, where a case study was carried out, with the planning of a Thematic Workshop together with graduates in chemistry, members of PIBID, entitled “Spices: Chemistry present in ...
Martins, Joana Laura de Castro   +3 more
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A Data-Based Hybrid Chemistry Acceleration Framework for the Low-Temperature Oxidation of Complex Fuels

open access: yesEnergies
The oxidation of complex hydrocarbons is a computationally expensive process involving detailed mechanisms with hundreds of chemical species and thousands of reactions.
Sultan Alqahtani   +2 more
doaj   +1 more source

Microscale Gas Chemistry

open access: yesEducación Química, 2018
This article starts with a historical overview of the chemistry of gases from the first mention of air by Empedocles down through Lavoisiers Oxygen Theory. Gas generating equipment is reviewed along the way.
Bruce Mattson
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

ACHIEVEMENTS OF THE INSTITUTE OF CHEMISTRY OF THE ACADEMY OF SCIENCES OF MOLDOVA AT 50 YEARS ANNIVERSARY [PDF]

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2009
This communication deals with the appearance and development of the research in the field of chemistry in the Republic of Moldova; at the beginning - in chemistry sections of Moldovan Branch of the USSR Academy of Sciences and then - at the Institute of ...
Tudor Lupascu   +3 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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