Results 141 to 150 of about 5,860,744 (317)

Hepatic steatosis in postmenopausal women is characterized by distinct serum extracellular vesicle proteomic signatures

open access: yesBMC Medicine
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is common among midlife women. Circulating extracellular vesicles (EVs) carry bioactive cargo that may mediate or reflect disease processes, but their role in hepatic steatosis ...
Patrick Pirrotte   +11 more
doaj   +1 more source

Combined Detection Model for Criminal Network Detection

open access: yes, 2010
Detecting criminal networks from arrest data and offender demographics data made possible with our previous models such as GDM, OGDM, and SoDM and each of them proved successful on different types of criminal networks. To benefit from all features of police arrest data and offender demographics, a new combined model is developed and called as combined ...
Fatih Özgül   +3 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Principles of bacterial detection [PDF]

open access: yes, 2020
This work is a comprehensive approach to bacterial detection requiring a thorough knowledge of the subject and an effective integration of other disciplines in ..
Hughes, MP, Hoettges, K
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Seamless Detection: Unifying Salient Object Detection and Camouflaged Object Detection

open access: yesExpert Systems with Applications
Achieving joint learning of Salient Object Detection (SOD) and Camouflaged Object Detection (COD) is extremely challenging due to their distinct object characteristics, i.e., saliency and camouflage. The only preliminary research treats them as two contradictory tasks, training models on large-scale labeled data alternately for each task and assessing ...
Yi Liu 0038   +6 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Floating Small Target Identification Method Based on Doppler Time Series Information

open access: yesRemote Sensing
Traditional radar detection methods heavily rely on the signal-to-clutter ratio (SCR); a variety of feature-based detection methods have been proposed, providing a new way for radar detection and the recognition of weak targets.
Hengli Yu   +5 more
doaj   +1 more source

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