Results 191 to 200 of about 15,552,862 (368)

Adaptive Change-Point Detection for Studying Human Locomotion

, 2021
Sylvain Jung, Laurent Oudre, Charles Truong, Eric Dorveaux, Louis Gorintin, Nicolas Vayatis, Damien Ricard   +6 more
openalex   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

ReninAngiotensinAldosterone System Gene Polymorphisms and Coronary Artery Disease: Detection of Gene-Gene and Gene-Environment Interactions

, 2012
En‐Zhi Jia, Zhenxia Xu, Chang–Yan Guo, Li Li, Yan Gu, Tiebing Zhu, Lian‐Sheng Wang, Kejiang Cao, Wen‐Zhu Ma, Zhijian Yang   +9 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A Dynamic Analysis Data Preprocessing Technique for Malicious Code Detection with TF-IDF and Sliding Windows [PDF]

Mihui Kim, Haesoo Kim
openalex   +1 more source

Detection of progressive macular thickness loss using optical coherence tomography in glaucoma suspect and glaucomatous eyes [PDF]

, 2012
Philip Niles, David S. Greenfield, Mitra Sehi, Namita Bhardwaj, Shawn M. Iverson, Young Seob Chung, Y S Chung   +6 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Detection of Citrus psorosis virus in field trees by direct tissue blot immunoasay in comparison with ELISA, symptomatology, biological indexing and cross-protection tests. [PDF]

, 2002
ALIOTO, DANIELA, GUERRI J., MARTIN S, MILNE RG, MORENO P.   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

fMRI-DTI modeling via landmark distance atlases for prediction and detection of fiber tracts

, 2011
Lauren J. O’Donnell, Laura Rigolo, Isaiah Norton, William M. Wells, Carl‐Fredrik Westin, Alexandra J. Golby   +5 more
openalex   +2 more sources