Results 251 to 260 of about 5,860,744 (317)

Early detection of dead broilers in commercial farms using temporal persistence of stationary behavior. [PDF]

Poult Sci
Park E, Song J.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

SCPA-Net: Text-Enhanced Cross-Platform Framework with Semantic Consistency Enhancement for Pine Wilt Detection. [PDF]

Plants (Basel)
He S, Zhao W, Wang P, He M.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Direct all-electrical decoding of vector vortex beams on chip. [PDF]

Sci Adv
Dai M, Zhang X, Chen W, Wang C, Wang Q, Wang QJ.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Highly sensitive X-ray detectors with polymer-perovskite-embedded flexible teflon membranes.

Mater Horiz
Sarisozen S, Lehnen AC, Hu F, Ofkeli G, von Reppert A, Rössle M, Ozen S, Kaya S, Holte L, Maslyanchuk O, Groszewicz PB, Hartlieb M, Neher D, Lang F.   +13 more
europepmc   +1 more source

Advancements in Nanomaterial-Based Biosensors for Neuropsychiatric and Neurodegenerative Diagnostics: From Biomarker Discovery to Clinical Translation. [PDF]

Biosensors (Basel)
Li X, Han X, Han Q, He X, Huang Y, Liu A.   +5 more
europepmc   +1 more source

Position Statement on Noninvasive Seizure Detection/Alerting Devices: A Joint Statement of the American Epilepsy Society, the Epilepsy Foundation, and the Danny Did Foundation. [PDF]

Epilepsy Curr
Grzeskowiak C, Alick-Lindstrom S, Bari AA, Farrenburg M, Fong-Isariyawongse J, Henninger H, Jewell A, Orciuoli L, Pellinen J, Stanton T, Hopp JL, French JA.   +11 more
europepmc   +1 more source