Results 281 to 290 of about 15,552,862 (368)

Role of Detection of Early Response of Apoptosis in Patient Selection for Continuation of Preoperative Chemoradiation Therapy for Lower Rectal Cancer.

, 2000
Y. Ogata, Shunsuke Mori, Yoshito Akagi, H Kamei, K. Tokuhara, Yasunari Miyagi, M. Kanazawa, Yasuhiro Nozoe, Hitoshi Oda, Kiyohisa INUZUKA, NAOFUMI HAYABUTI, Kazuo Shirouzu   +11 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A self-attention driven multi-scale object detection framework for adverse weather in smart cities. [PDF]

Sci Rep
Dasu BT, Reddy MV, Kumar KV, Chithaluru P, Ahmed N, Abd Elminaam DS.   +5 more
europepmc   +1 more source

STUDY TO CRACK DETECTION USING FLOODLIGHT

, 2011
Masando SHIOZAKI, Noriaki Kikuchi, Norishige MAEKAWA, Shigeki MASUYAMA, Tetsuhiro Ishizaka, Tatsunori Sada   +5 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Multi-channel SAR Ground Moving Target Detection Based on Multistage Wiener Filter

, 2011
Bin Tian, Daiyin Zhu, Di Wu, Zhaoda Zhu
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

FF-Mamba-YOLO: An SSM-Based Benchmark for Forest Fire Detection in UAV Remote Sensing Images. [PDF]

J Imaging
Guo B, Liu D, Shen Z, Wang T.
europepmc   +1 more source