Results 271 to 280 of about 11,794,013 (339)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

FLF-RCNN: A Fine-Tuned Lightweight Faster RCNN for Precise and Efficient Industrial Quality Inspection. [PDF]

Sensors (Basel)
An N, Yang Z, Wan L, Li J, Wang Y.
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

POLD-YOLO: A Lightweight YOLO11-Based Algorithm for Insulator Defect Detection in UAV Aerial Images. [PDF]

Sensors (Basel)
Hu B, Wu F, Zhang P, Cui J, Liu Y.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

YOLO-MFD: a multi-scale feature and dynamic head framework for prefabricated shoreline underwater object detection. [PDF]

Sci Rep
Gang Y, Li T, Li S, Shang Y.
europepmc   +1 more source

Design of an automated cell batch microinjection system based on magnetic tweezers for zebrafish embryos. [PDF]

Microsyst Nanoeng
Guo X, Wang F, Zhao A, Zhang Y, Jiang H, Knoll A, Shen M, Lv F, Zhou M.   +8 more
europepmc   +1 more source

A Novel Fluorescence-Triggered Auditory Feedback Photosensor for Precision Lymph Node Mapping. [PDF]

Sensors (Basel)
Yoon K, Son H, Kang H, Lee S, Lee TH, Lee WS, Kim KG.   +6 more
europepmc   +1 more source

Real-Time Intelligent Detection Algorithm for Ship Targets in High-Resolution Wide-Swath Sea Surface Images Captured by Airborne Cameras. [PDF]

Sensors (Basel)
Liu H, Fu Q, Wang H, Zhou H, Li Y, Jiang H.   +5 more
europepmc   +1 more source

Effects of two side-by-side camera trap deployments on estimations of richness, abundance, and the detection of medium- and large-sized mammals. [PDF]

PLoS One
Guerrero-Vázquez S, Zalapa SS, Mandujano S, Basilio-Barrera AS, Pérez-Moreno M.   +4 more
europepmc   +1 more source