Results 41 to 50 of about 26,354 (218)

Tumor Exosome Mimicking Nanoparticles for Tumor Combinatorial Chemo-Photothermal Therapy

Frontiers in Bioengineering and Biotechnology, 2020
The development of biomimetic nanoparticles with functionalities of natural biomaterial remains a major challenge in cancer combination therapy. Herein, we developed a tumor-cell-derived exosome-camouflaged porous silicon nanoparticles (E-MSNs) as a drug
Ran Tian, Ran Tian, Ran Tian, Zhaosong Wang, Ruifang Niu, Hanjie Wang, Hanjie Wang, Weijiang Guan, Jin Chang, Jin Chang   +9 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Coordinated synthesis of aromatic amino acid derived pigments in yeast via global transcriptional engineering

Microbial Cell Factories
Background Rational metabolic pathway engineering is capable of boosting upstream flux towards downstream synthesis of target products, such as aromatic amino acid derivatives.
Huimin Xue, Mingshan Li, Yuhui Cui, Dongkui Tian, Duo Liu, Hanjie Wang   +5 more
doaj   +1 more source

Strip steel surface defect detection based on lightweight YOLOv5

Frontiers in Neurorobotics, 2023
Deep learning-based methods for detecting surface defects on strip steel have advanced detection capabilities, but there are still problems of target loss, false alarms, large computation, and imbalance between detection accuracy and detection speed.
Yongping Zhang, Sijie Shen, Sen Xu
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

On Detecting Regularity of Functions: A Probabilistic Analysis

Journal of Complexity, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Feng Gao 0002, Grzegorz W. Wasilkowski
openaire   +1 more source

Common ground: Efficient, consistent, observer‐independent bioacoustic call density estimation with adjudicated ground truth and capture–recapture detection functions

Methods in Ecology and Evolution
Passive acoustic recording is a cost‐effective method for monitoring vocal animals. Within this field, there is an increasing focus on automated detection algorithms for counting calls and estimating call density (in space and time).
Brian S. Miller, Nat Kelly, Meghan G. Aulich, Naysa Balcazar, Susannah Buchan, Franciele R. deCastro, Kym Reeve, Danielle V. Harris   +7 more
doaj   +1 more source

Hypoxia-induced reprogramming of glucose-dependent metabolic pathways maintains the stemness of human bone marrow-derived endothelial progenitor cells

Scientific Reports, 2023
The benefits of hypoxia for maintaining the stemness of cultured human bone marrow-derived endothelial progenitor cells (BM EPCs) have previously been demonstrated but the mechanisms responsible remain unclear.
Dongni Lin, Kaihao Yan, Lingyun Chen, Junxiong Chen, Jianing Xu, Zijing Xie, Zhujun Li, Shuo Lin, Jinghuan Li, Zhenzhou Chen   +9 more
doaj   +1 more source