Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Joint Probabilistic Data Association Filter with Unknown Detection Probability and Clutter Rate. [PDF]
He S, Shin HS, Tsourdos A.
europepmc +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Signal coverage approach to the detection probability of hypothetical extraterrestrial emitters in the Milky Way. [PDF]
Grimaldi C.
europepmc +1 more source
Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen +6 more
wiley +1 more source
Environmental DNA (eDNA) Detection Probability Is Influenced by Seasonal Activity of Organisms. [PDF]
de Souza LS +3 more
europepmc +1 more source
Approximation of binomial probability function for a normal probability function
Educação Superior::Ciências Exatas e da Terra::MatemáticaThe digital animation presents the approximation of the function of the binomial probability for a function of normal probability, also known as Gaussian distribution.
Rojo, Isabel Martín +3 more
core
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Compensating for geographic variation in detection probability with water depth improves abundance estimates of coastal marine megafauna. [PDF]
Hagihara R +5 more
europepmc +1 more source
Insurance and Probability Weighting Functions [PDF]
Evidence shows that (i) people overweight low probabilities and underweight high probabilities, but (ii) ignore events of extremely low probability and treat extremely high probability events as certain.
Ali al-Nowaihi, Sanjit Dhami
core

