FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Analysis of optimal detection range performance of LiDAR systems applying coaxial optics. [PDF]
Heliyon, 2022 Kim DL, Park HW, Yeon YM.
europepmc +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A Dual-Encoded Bead-Based Immunoassay with Tunable Detection Range for COVID-19 Serum Evaluation. [PDF]
Angew Chem Int Ed Engl, 2022 Lin Z +6 more
europepmc +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Beni-Suef University Journal of Basic and Applied SciencesBackground Climate change significantly influences the geographical distribution of plant species worldwide, especially endemics. Endemic species are plants that live in limited distribution ranges of unique ecology and, thus, are the most vulnerable ...
Aliaa Muhammad Refaat +3 more
doaj +1 more source
Nickel-based electrochemical sensor with a wide detection range for measuring hydroxyl ions and pH sensing. [PDF]
J Electroanal Chem (Lausanne), 2021 Jafari B, Muthuvel M, Botte GG.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A fine single Pd microwire H2 sensor fabricated by using a femtosecond laser for a wide detection range at room temperature. [PDF]
Nanoscale Adv, 2022 Zhu H, Dai YZ, Sun XC, Xia H.
europepmc +1 more source
ADRPM-VII applied to the long-range acoustic detection problem [PDF]
An acoustic detection range prediction model (ADRPM-VII) has been written for IBM PC/AT machines running on the MS-DOS operating system. The software allows the user to predict detection distances of ground combat vehicles and their associated targets ...
Koenig, Gerald, Shalis, Edward
core +1 more source