Results 111 to 120 of about 1,375,201 (314)

Comparison of self-referencing techniques for photothermal detection of trace compounds in water [PDF]

, 2000
Self-referencing techniques are compared for a closed-cell photothermal detector that uses a water meniscus as a pressure sensor. Deflection of the meniscus was measured using an optical fibre Fabry–Perot interferometer.
Johnson, Mark, Jane Hodgkinson, Hodgkinson, J., Hodgkinson, Jane, Johnson, M., Dakin, J.P., Dakin, John P., Mark Johnson, John P Dakin   +8 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An exploration of vibration based damage detection techniques for composite materials

Structural damage monitoring is inevitable for the structures to perform during their intended service life adroitly. In the present review, literature related to techniques for diagnosing vibration-intensive damages have been evaluated in order to ...
Firoj Umraobhai Pathan, Milind Motiram Patil, Prasad Ramchandra Baviskar, Vishnu S. Aher   +3 more
core   +1 more source

Deepfake-Driven Social Engineering: Threats, Detection Techniques, and Defensive Strategies in Corporate Environments

Journal of Cybersecurity and Privacy
The evolution of deepfake technology has the potential to reshape the threat landscape in corporate environments by enabling highly convincing digital impersonations.
Kristoffer Torngaard Pedersen, Lauritz Pepke, Tobias Stærmose, Maria Papaioannou, Gaurav Choudhary, Nicola Dragoni   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Edge Detection Techniques for Quantifying Spatial Imaging System Performance and Image Quality [PDF]

, 2019
Measuring camera system performance and associating it directly to image quality is very relevant, whether images are aimed for viewing, or as input to machine learning and automated recognition algorithms.
Oliver van Zwanenberg, Robin Jenkin, Triantaphillidou, S., Sophie Triantaphillidou, Jenkin, R., Van Zwanenberg, O., Psarrou, A., Alexandra Psarrou   +7 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Research progress on the N protein of porcine reproductive and respiratory syndrome virus

Frontiers in Microbiology
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease caused by the porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV exhibits genetic diversity and complexity in terms of immune responses, posing challenges
Yajie Zheng, Gan Li, Qin Luo, Huiyang Sha, Hang Zhang, Ruining Wang, Weili Kong, Jiedan Liao, Mengmeng Zhao   +8 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source