Results 151 to 160 of about 1,375,201 (314)
Evaluating and combining digital video shot boundary detection algorithms [PDF]
, 2000 The development of standards for video encoding coupled with the increased power of computing mean that content-based manipulation of digital video information is now feasible.
Murphy, Noel +6 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Detection, molecular function and mechanisms of m5C in cancer
Clinical and Translational MedicineInterest in RNA posttranscriptional modifications, particularly 5‐methylcytosine (m5C), has surged in recent years. Studies have shown that m5C plays a key role in cellular processes and is closely linked to tumourigenesis.
Linhui Zhang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Automated Detection of Usage Errors in non-native English Writing
, 2011 In an investigation of the use of a novelty detection algorithm for identifying inappropriate word combinations in a raw English corpus, we employ an unsupervised detection algorithm based on the one- class support ...
Fujishima, Satoru, Ishizaki, Shun
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Anomaly intrusion detection model using data mining techniques
, 2006 Intrusion detection system has become an important component of a network infrastructure protection mechanism. There are generally two main methods or techniques in intrusion detection; misuse detection and anomaly detection.
Rusli, Rozana, Abdullah, Abdul Hanan
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Breast tumour detection using a flat 16 element array
, 2005 A new experimental prototype of a breast cancer detection technique using real aperture multi-static radar is presented. The system comprises a fully-populated 16 element flat array and an associated system to switch between different transmit and ...
Preece, A +6 more
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