Results 181 to 190 of about 1,375,201 (314)

Quantum-Scale Friction at Solid-Liquid Interface: Simulation, Detection Techniques, Mechanisms, and Emerging Applications. [PDF]

Nanomicro Lett
Han Y, Zhang R, Liu D, Luo J.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Enhancing Leukemia Detection: An Automated Approach Using Deep Learning and Ensemble Techniques

As leukemia ranks high among the global causes of death, it's crucial to identify it early to enhance the prognosis for patients. The majority of diagnostic processes used today rely on medical experts inspecting samples manually.
Mian Qaisar, Saeed, Rabeea Jaffari, Lee Yu Jen, Humaira Nisar, Saad Ahmed Syed, Yan Chai Hum   +5 more
core  

A comprehensive review of ball detection techniques in sports. [PDF]

PeerJ Comput Sci
Moreira C, Ferreira L, Coelho PJ.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Detection techniques for tomato diseases under non-stationary climatic conditions. [PDF]

Front Plant Sci
Wu Z, Han J, Wang S, Meng X, Fu R.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Tackling toxicity in Arabic social media through advanced detection techniques. [PDF]

Sci Rep
Hatem L, Omar A, Ali AA, Farghaly HM.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Artificial Intelligence-Powered Chronic Obstructive Pulmonary Disease Detection Techniques-A Review. [PDF]

Diagnostics (Basel)
Sait ARW, Shaikh MA.
europepmc   +1 more source